Mouse Anti-IL18R1 Recombinant Antibody; Fab Fragment (TAB-210CT-F(E))
CAT#: TAB-210CT-F(E)
This product is a recombinant mouse antibody Fab fragment that recognizes IL-18R1 or IL-18Rα (interleukin-18R1 or interleukin-18Rα). The antibody was purified by affinity chromatography.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7615/if_selected.jpg
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Specifications
- Immunogen
- DNA plasmid expressing both chains (alpha and beta) of human IL-18 receptor
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human IL-18R1 or IL-18Rα (interleukin-18R1 or interleukin-18Rα)
- Species Reactivity
- Human, Monkey
- Applications
- Used for immunoassay techniques such as: Flow Cytometry; Enzyme-linked Immunosorbent Assay; Ibhibition
- Related Disease
- Chronic obstructive pulmonary disease (COPD)
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Gene ID
- 8809
- UniProt ID
- Q13478
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Related Signaling Pathways
TNF Signaling Pathway
Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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