Mouse Anti-IL1RL2 Recombinant Antibody (TAB-0534CL)
CAT#: TAB-0534CL
This product is a recombinant mouse antibody that recognizes human interleukin 1 receptor-like 2 (IL1RL2). The antibody was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography. Kinetics and binding affinity of this antibody binding to recombinant human ILIRL2 was measured by the BLI and the KD value is 16 pM.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (A-431, ASC TERT1, HaCaT, HSkMC, hTCEpi)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115598-IL1RL2
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Specifications
- Immunogen
- Recombinantly produced human IL-36R (ECD-extracellular domain: amino acids 20-332 of Genbank Accession #NP_003845) protein
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human IL1RL2
- Species Reactivity
- Human
- Applications
- ELISA, Inhib
- Related Disease
- Epithelial-mediated inflammation/fibrosis in diseases such as psoriasis, inflammatory bowel disease, scleroderma, COPD, and chronic kidney disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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High Affinity Binding
The binding kinetics of this antibody are impressive. With a KD value of 16 pM measured by BLI, it provided high-sensitivity detection of IL1RL2 in our ELISA setups. It was crucial for our work on the IL-1 receptor family.
Validated For Inhibition
Beyond standard binding, we found this antibody useful for inhibition studies involving the IL-36 receptor pathway. The recombinant production ensures that we get the same high-quality mouse antibody with every batch, which is vital for our inflammation research.
Q&As
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What is the binding affinity of this antibody?
A: We have measured the kinetics and binding affinity of this recombinant mouse antibody using Bio-Layer Interferometry (BLI). The dissociation constant (KD) value for binding to recombinant human IL1RL2 is 16 pM, indicating a very high affinity for the target receptor.
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What is the immunogen used for this antibody?
A: The antibody was produced using a recombinantly produced human IL-36R protein. Specifically, the immunogen consists of the extracellular domain (ECD), corresponding to amino acids 20-332 of the protein. It specifically recognizes human interleukin 1 receptor-like 2.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "IL1RL2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-561 | Recombinant Anti-human IL1RL2 Antibody | ELISA, WB, IF, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-561-F(E) | Recombinant Anti-human IL1RL2 Antibody Fab Fragment | IF, FC, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-561-S(P) | Recombinant Anti-human IL1RL2 Antibody scFv Fragment | Neut, IF, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-561 | Recombinant Human Anti-human IL1RL2 Antibody | ELISA, WB, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-561-F(E) | Recombinant Human Anti-human IL1RL2 Antibody Fab Fragment | IP, RIA, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-561-S(P) | Recombinant Human Anti-human IL1RL2 Antibody scFv Fragment | FC, IP, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0535CL | Mouse Anti-IL1RL2 Recombinant Antibody (TAB-0535CL) | ELISA, Inhib | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0536CL | Mouse Anti-IL1RL2 Recombinant Antibody (TAB-0536CL) | ELISA, Inhib | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0537CL | Mouse Anti-IL1RL2 Recombinant Antibody (TAB-0537CL) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0538CL | Mouse Anti-IL1RL2 Recombinant Antibody (TAB-0538CL) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0539CL | Mouse Anti-IL1RL2 Recombinant Antibody (TAB-0539CL) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0726-WJ | Human Anti-IL1RL2 Recombinant Antibody (HPAB-0726-WJ) | ELISA | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0727-WJ | Human Anti-IL1RL2 Recombinant Antibody (HPAB-0727-WJ) | ELISA | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0728-WJ | Human Anti-IL1RL2 Recombinant Antibody (HPAB-0728-WJ) | ELISA | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0726-WJ-F(E) | Human Anti-IL1RL2 Recombinant Antibody; Fab Fragment (HPAB-0726-WJ-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0727-WJ-F(E) | Human Anti-IL1RL2 Recombinant Antibody; Fab Fragment (HPAB-0727-WJ-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0728-WJ-F(E) | Human Anti-IL1RL2 Recombinant Antibody; Fab Fragment (HPAB-0728-WJ-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0726-WJ-S(P) | Human Anti-IL1RL2 Recombinant Antibody; scFv Fragment (HPAB-0726-WJ-S(P)) | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0727-WJ-S(P) | Human Anti-IL1RL2 Recombinant Antibody; scFv Fragment (HPAB-0727-WJ-S(P)) | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0728-WJ-S(P) | Human Anti-IL1RL2 Recombinant Antibody; scFv Fragment (HPAB-0728-WJ-S(P)) | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC332 | Recombinant Anti-IL1RL2 Vesicular Antibody, EV Displayed (VS-0425-YC332) | ELISA, FC, Inhib, Cell-uptake |
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