Afuco™ Anti-IL4R Recombinant Antibody (AFC-416CL), ADCC Enhanced
CAT#: AFC-416CL
Anti-IL4R ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. It is a fully human monoclonal antibody to IL-4Ralpha that blocks both IL-4 and IL-13 pathways.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to nucleoplasm, plasma membrane & centriolar satellites.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/70380/1812_F10_5_cr59ef13a97c5ff_selected.jpg
Normal Tissue
Figure 2 Tonsil
High expression in tonsil
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50124/ihc_selected.jpg
Normal Tissue
Figure 3 IHC staining of human tonsil
Immunohistochemical staining of human tonsil shows distinct cytoplasmic positivity in subsets of cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4451/ihc_selected.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50124/123264_A_9_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50124/123264_A_8_5.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (Daudi, HBEC3-KT, HDLM-2, U-698)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000077238-IL4R
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Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- Human IgG1
- Species Reactivity
- Human
- Applications
- ELISA, WB
- Related Disease
- Asthma
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Cha***s21.Apr,24
Outstanding ELISA Results with Afuco® Anti-IL4R Recombinant Antibody (AFC-416CL), ADCC Enhanced (AFC-416CL).
We are extremely pleased with the ELISA results for your Afuco® Anti-IL4R Recombinant Antibody (AFC-416CL), ADCC Enhanced (AFC-416CL). The remarkably low EC₅₀ of 4.3 ng/mL highlights its exceptionally high affinity for human IL4R, significantly exceeding our expectations. This high-quality antibody will be invaluable for our research on IL4R binding and signaling. Thank you for providing such an efficient and excellent product; we are very satisfied.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L079E | IL4-PE immunotoxin | Cytotoxicity assay, Functional assay | |
| AGTO-L079D | IL4-DT immunotoxin | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0003CL | Anti-Human IL4R Recombinant Antibody (6-2) | Inhib, RIA, ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0004CL | Anti-Human IL4R Recombinant Antibody (12B5) | Inhib, RIA, ELISA, Block | Human antibody |
| TAB-0005CL | Anti-Human IL4R Recombinant Antibody (27A1) | Block, Inhib, ELISA | |
| TAB-0006CL | Anti-Human IL4R Recombinant Antibody (5A1) | Block, Inhib, ELISA | |
| TAB-0007CL | Anti-Human IL4R Recombinant Antibody (63) | Block, Inhib, ELISA | |
| TAB-0008CL | Anti-Human IL4R Recombinant Antibody (1B7) | Block, Inhib, ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1432CQ | Mouse Anti-IL4R Recombinant Antibody (clone CBL439) | WB, FC, IHC, CyTOF, Neut | Mouse IgG2a |
| NEUT-1433CQ | Mouse Anti-IL4R Recombinant Antibody (clone MM0405-4Y44) | WB, Neut, IHC, IHC-P | Mouse IgG1 |
| NEUT-1434CQ | Rabbit Anti-IL4R Recombinant Antibody (clone CBL1006) | Neut | Rabbit IgG |
| NEUT-1435CQ | Rabbit Anti-IL4R Recombinant Antibody (clone CBL998) | Neut | Rabbit IgG |
| NEUT-1436CQ | Mouse Anti-IL4R Recombinant Antibody (clone CBL075) | ELISA, Neut | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4007 | Rabbit Anti-Il4r Recombinant Antibody (clone SI69DS) | ELISA | Rabbit IgG |
| MOR-4274 | Rabbit Anti-IL4R Recombinant Antibody (clone SI357DS) | FC | Rabbit IgG |
| MOR-4275 | Rabbit Anti-IL4R Recombinant Antibody (clone SI358DS) | Neut | Rabbit IgG |
| MOR-4276 | Rabbit Anti-IL4R Recombinant Antibody (clone SI359DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0291-YC-F(E) | Human Anti-IL4R Recombinant Antibody (clone Antibody 1); Fab Fragment | HTRF, FuncS | Human Fab |
| HPAB-0344LY-F(E) | Human Anti-IL4R Recombinant Antibody; Fab Fragment (HPAB-0344LY-F(E)) | Block, ELISA | Human Fab |
| HPAB-0345LY-F(E) | Human Anti-IL4R Recombinant Antibody; Fab Fragment (HPAB-0345LY-F(E)) | Block, ELISA | Human Fab |
| HPAB-0346LY-F(E) | Human Anti-IL4R Recombinant Antibody; Fab Fragment (HPAB-0346LY-F(E)) | Block, ELISA | Human Fab |
| HPAB-0347LY-F(E) | Human Anti-IL4R Recombinant Antibody; Fab Fragment (HPAB-0347LY-F(E)) | Block, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0071-WJ-S(P) | Human Anti-IL4R Recombinant Antibody (HPAB-0071-WJ-S(P)); scFv Fragment | ELISA, WB | Human scFv |
| HPAB-0344LY-S(P) | Human Anti-IL4R Recombinant Antibody; scFv Fragment (HPAB-0344LY-S(P)) | Block, ELISA | Human scfv |
| HPAB-0345LY-S(P) | Human Anti-IL4R Recombinant Antibody; scFv Fragment (HPAB-0345LY-S(P)) | Block, ELISA | Human scfv |
| HPAB-0346LY-S(P) | Human Anti-IL4R Recombinant Antibody; scFv Fragment (HPAB-0346LY-S(P)) | Block, ELISA | Human scfv |
| HPAB-0347LY-S(P) | Human Anti-IL4R Recombinant Antibody; scFv Fragment (HPAB-0347LY-S(P)) | Block, ELISA | Human scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FN-256CQ | Mouse Anti-IL4R Recombinant Antibody (clone CBL-1350) | FC, FuncS | Mouse IgG1, κ |
| HPAB-1244-FY | Human Anti-IL4R Recombinant Antibody (HPAB-1244-FY) | ELISA, WB | Human IgG |
| HPAB-1245-FY | Human Anti-IL4R Recombinant Antibody (HPAB-1245-FY) | ELISA, WB | Human IgG |
| HPAB-1246-FY | Human Anti-IL4R Recombinant Antibody (HPAB-1246-FY) | ELISA, WB | Human IgG |
| HPAB-1247-FY | Human Anti-IL4R Recombinant Antibody (HPAB-1247-FY) | ELISA, WB | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY132 | Human Anti-IL4R (clone 12B5) scFv-Fc Chimera | Block | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC103 | Recombinant Anti-IL4R Vesicular Antibody, EV Displayed (VS-0425-YC103) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3535 | Anti-IL4R Immunohistochemistry Kit | IHC |
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