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Recombinant Mouse Anti-INSR Soluble TCR (clone 2C) (CAT#: scTCR-160CQ-S(P))

Recombinant Mouse single-chain TCR (scTCR) 2C recognizes INSR peptide (GNYSFYAL) in the context of H-2Kb. The scTCR is responsible for the specificity of T cells.


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Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36303/737_C10_2_selected.jpg
Figure 2 IHC staining of human liver
Figure 2 IHC staining of human liver
(Immunohistochemical staining of human liver shows moderate cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36302/ihc_selected.jpg
Figure 3 IF staining of human cell line A-431
Figure 3 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36303/836_E10_2_blue_red_green.jpg
Normal Tissue
Figure 4 Colon
Figure 4 Colon
(landular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36302/112008_A_9_3.jpg
Figure 5 Liver
Figure 5 Liver
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36302/112008_A_8_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36302/112008_A_7_5.jpg
Figure 7 Testis
Figure 7 Testis
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36302/112008_A_6_6.jpg
Figure 8 Skeletal muscle
Figure 8 Skeletal muscle
(Myocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36302/112008_B_3_6.jpg
Figure 9 Lymph node
Figure 9 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36302/112008_A_8_8.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (Karpas-707, U-266/70)
Figure 10 RNA cell line category: Cell line enhanced (Karpas-707, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000171105-INSR
Figure 10 RNA cell line category: Cell line enhanced (Karpas-707, U-266/70)
Figure 10 RNA cell line category: Cell line enhanced (Karpas-707, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000171105-INSR

Specifications

  • Host Species
  • Mouse
  • Target
  • INSR
  • Species Reactivity
  • Mouse
  • Epitope
  • GNYSFYAL
  • MHC
  • H-2Kb
  • Clone
  • 2C
  • Type
  • Single-Chain TCR
  • Related Disease
  • Type 1 diabetes

Target

  • Alternative Names
  • INSR; Insulin receptor; IR; IR-A; IR-B; CD220; 4932439J01Rik; D630014A15Rik

Related Resources

  • Related Signaling Pathways
  • Related Diseases

Downloads

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Recombinant Antibody

CAT Product Name Application Type
MOB-1236z Mouse Anti-INSR Recombinant Antibody (clone 25F8) ELISA, FC, ICC, IF, IHC, FuncS Mouse IgG1, κ
PABL-246 Mouse Anti-INSR Recombinant Antibody (clone 83-7) WB, ELISA, FuncS Mouse IgG
HPAB-2351LY Human Anti-INSR Recombinant Antibody (HPAB-2351LY) ELISA, WB, FC, FuncS Humanized IgG
HPAB-2352LY Human Anti-INSR Recombinant Antibody (HPAB-2352LY) ELISA, WB, FC, FuncS Humanized IgG
HPAB-2353LY Human Anti-INSR Recombinant Antibody (HPAB-2353LY) ELISA, WB Humanized IgG

Rat Antibody

CAT Product Name Application Type
TAB-441CL Human Anti-INSR Recombinant Antibody (TAB-441CL) ELISA Human IgG

scFv Fragment Antibody

CAT Product Name Application Type
PSBL-246 Mouse Anti-INSR Recombinant Antibody (clone 83-7); scFv Fragment WB, ELISA, FuncS Mouse scFv
PSBZ-083 Mouse Anti-INSR Recombinant Antibody (clone 83-14); scFv Fragment WB, FuncS Mouse scFv
HPAB-0129-YC-S(P) Mouse Anti-INSR Recombinant Antibody; scFv Fragment (HPAB-0129-YC-S(P)) ELISA, FC Mouse scFv
HPAB-2351LY-S(P) Human Anti-INSR Recombinant Antibody; scFv Fragment (HPAB-2351LY-S(P)) ELISA, WB Humanized scfv
HPAB-2352LY-S(P) Human Anti-INSR Recombinant Antibody; scFv Fragment (HPAB-2352LY-S(P)) ELISA, WB Humanized scfv

Fab Fragment Antibody

CAT Product Name Application Type
PFBL-246 Mouse Anti-INSR Recombinant Antibody (clone 83-7); Fab Fragment WB, ELISA, FuncS Mouse Fab
HPAB-0129-YC-F(E) Mouse Anti-INSR Recombinant Antibody; Fab Fragment (HPAB-0129-YC-F(E)) ELISA, FC Mouse Fab
HPAB-2351LY-F(E) Human Anti-INSR Recombinant Antibody; Fab Fragment (HPAB-2351LY-F(E)) ELISA, WB Humanized Fab
HPAB-2352LY-F(E) Human Anti-INSR Recombinant Antibody; Fab Fragment (HPAB-2352LY-F(E)) ELISA, WB Humanized Fab
HPAB-2353LY-F(E) Human Anti-INSR Recombinant Antibody; Fab Fragment (HPAB-2353LY-F(E)) ELISA, WB Humanized Fab

Human Antibody

CAT Product Name Application Type
TAB-711LC Human Anti-INSR Recombinant Antibody (TAB-711LC) ELISA, FC, FuncS Human IgG
TAB-711LC-S(P) Human Anti-INSR Recombinant Antibody; scFv Fragment (TAB-711LC-S(P)) ELISA, FC Human scFv
TAB-712LC-S(P) Human Anti-INSR Recombinant Antibody; scFv Fragment (TAB-712LC-S(P)) ELISA, FC Human scFv
TAB-711LC-F(E) Human Anti-INSR Recombinant Antibody; Fab Fragment (TAB-711LC-F(E)) ELISA, FC Human Fab
TAB-712LC-F(E) Human Anti-INSR Recombinant Antibody; Fab Fragment (TAB-712LC-F(E)) ELISA, FC Human Fab

Mouse Antibody

CAT Product Name Application Type
PABX-124 Recombinant Mouse Anti-IR Antibody (Fab83-14) Neut, FuncS IgG
PABX-125 Recombinant Mouse Anti-IR Antibody (Fab83-7) WB, ELISA, FuncS IgG
PABX-124-F (E) Recombinant Mouse Anti-IR Antibody Fab Fragment (Fab83-14 ) Neut, FuncS Fab
PABX-125-F (E) Recombinant Mouse Anti-IR Antibody Fab Fragment (Fab83-7 ) WB, ELISA, FuncS Fab

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC1205 PE-H-2Kb/Mouse Insr (GNYSFYAL) MHC Tetramer FCM
MHC-LC1206 APC-H-2Kb/Mouse Insr (GNYSFYAL) MHC Tetramer FCM
MHC-LC1207 BV421-H-2Kb/Mouse Insr (GNYSFYAL) MHC Tetramer FCM

Blocking Antibody

CAT Product Name Application Type
NEUT-1533CQ Mouse Anti-INSR Recombinant Antibody (clone 1.B.109) Inhib, IP Mouse IgG2a
NEUT-1535CQ Mouse Anti-INSR Recombinant Antibody (clone 47-9) FC, Block, WB Mouse IgG1
NEUT-1536CQ Mouse Anti-INSR Recombinant Antibody (clone 18-44) FC, ICC, IF, Block, FuncS, IP, WB Mouse IgG2b

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1534CQ Mouse Anti-INSR Recombinant Antibody (clone 29B4) IP, Neut Mouse IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1844 Rabbit Anti-INSR Recombinant Antibody (clone DS1844AB) ICC, IP, WB Rabbit IgG
MOR-4630 Rabbit Anti-INSR Recombinant Antibody (clone TH143DS) WB Rabbit IgG
MOR-4688 Rabbit Anti-INSR Recombinant Antibody (clone TH202DS) WB, FC Rabbit IgG

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