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    Afuco™ Anti-Human IRAK4 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-433CL)

    Anti-IRAK4 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibodies that bind phosphorylated forms of IRAK4, used for detecting, diagnosing, and prognosticating immune diseases and disorders such as inflammation, autoimmune disorders, and recurrent bacterial infections.

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    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    Purity :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line A-431
    Figure 1 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane, cytosol & microtubules.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/16685/if_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nucleoli, cytosol & microtubules.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/621_E10_5_selected.jpg
    Normal Tissue
    Figure 3 IHC staining of human colon
    Figure 3 IHC staining of human colon
    (Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells and smooth muscle cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/16685/ihc_selected.jpg
    Figure 4 IHC staining of human breast
    Figure 4 IHC staining of human breast
    (Immunohistochemical staining of human breast shows strong cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/ihc_selected.jpg
    Figure 5 Cerebral cortex
    Figure 5 Cerebral cortex
    (nuclear Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/49420_B_8_5.jpg
    Figure 6 Pancreas
    Figure 6 Pancreas
    (Exocrine glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Pancreatic endocrine cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/49420_A_1_3.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/16685/37917_A_7_5.jpg
    Figure 8 Testis
    Figure 8 Testis
    (Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/22077/49420_A_6_6.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enhanced (U-937)
    Figure 9 RNA cell line category: Cell line enhanced (U-937)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198001-IRAK4

    Specifications

    • Host Species
    • Mouse
    • Type
    • ADCC enhanced antibody
    • Species Reactivity
    • Human
    • Related Disease
    • Immune Diseases

    Product Property

    • Purity
    • >97%, by SDS-PAGE under reducing conditions
    • Storage
    • Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.

    Target

    • Alternative Names
    • IRAK4; interleukin-1 receptor-associated kinase 4; IPD1; REN64; IRAK-4; NY-REN-64; renal carcinoma antigen NY-REN-64

    Related Resources

    • Related Signaling Pathways
    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "IRAK4"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Mouse Antibody Products Rabbit Monoclonal Antibody Products Non-Human Primate (NHP) Antibody Products
    CAT Product Name Application Type
    MOB-2079z Mouse Anti-IRAK4 Recombinant Antibody (clone 27A3) WB, ELISA, FC, IHC Mouse IgG1
    MOB-0992CT Recombinant Mouse anti-Human IRAK4 Monoclonal antibody (A8A8) ELISA, IHC-P, WB
    ZG-0770J Rabbit Anti-IRAK4 Recombinant Antibody (clone 10H4) ELISA, WB, FC Rabbit IgG
    VS3-FY761 Recombinant Rabbit Anti-IRAK4 Antibody (clone R01-1B2) WB, IHC-Fr, IHC-P, ICC, IF Rabbit IgG
    VS7-0425-WR149 Mouse Anti-IRAK4 Monoclonal Antibody (VS7-0425-WR149) WB, IHC-P, IF, FC, ELISA Mouse IgG

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