Afuco™ Anti-Human ITGA1 ADCC Recombinant Antibody (SAN-300), ADCC Enhanced
CAT#: AFC-435CL
Anti-ITGA1 ADCC Enhanced Antibody (SAN-300) is an ADCC enhanced antibody produced by our Afuco™ platform. SAN-300 is an investigational humanized anti-VLA-1 monoclonal antibody and an inhibitor of VLA-1, also known as α1β1 integrin. SAN-300 has potential application in multiple inflammatory and autoimmune diseases, including rheumatoid arthritis, inflammatory bowel disease, psoriasis, asthma and organ transplantation.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human colon
Immunohistochemical staining of human colon shows moderate cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42555/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42555/91585_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42555/91585_A_7_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42555/91585_A_8_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42555/91585_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42555/91585_A_6_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (fHDF/TERT166, HHSteC, SH-SY5Y, WM-115)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000213949-ITGA1
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Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Inflammatory Diseases; Rheumatoid Arthritis
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "ITGA1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1649z | Mouse Anti-ITGA1 Recombinant Antibody (clone 40D8) | FC, IHC, IP | Mouse IgG1 |
| MOB-2124MZ | Recombinant Mouse Anti-Human ITGA1 Antibody (clone 0.U.74) | ELISA, ICC | Mouse antibody |
| HPAB-1764-FY | Human Anti-ITGA1 Recombinant Antibody (clone 3.40) | ELISA, FuncS | Human IgG4 |
| HPAB-1765-FY | Human Anti-ITGA1 Recombinant Antibody (clone 2.19) | ELISA, FuncS | Human IgG4 |
| HPAB-1766-FY | Human Anti-ITGA1 Recombinant Antibody (clone 7.22) | ELISA, FuncS | Human IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-453CL | Human Anti-ITGA1 Recombinant Antibody (TAB-453CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBW-108 | Mouse Anti-ITGA1 Recombinant Antibody (clone AQC2); Fab Fragment | ELISA | Mouse Fab |
| PFBC-132 | Mouse Anti-ITGA1 Recombinant Antibody (clone mAb6); Fab Fragment | ELISA | Mouse IgG |
| HPAB-1764-FY-S(P) | Human Anti-ITGA1 Recombinant Antibody (clone 3.40); Fab Fragment | ELISA, FuncS | Human Fab |
| HPAB-1765-FY-S(P) | Human Anti-ITGA1 Recombinant Antibody (clone 2.19); Fab Fragment | ELISA, FuncS | Human Fab |
| HPAB-1766-FY-S(P) | Human Anti-ITGA1 Recombinant Antibody (clone 7.22); Fab Fragment | ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBW-108 | Mouse Anti-ITGA1 Recombinant Antibody (clone AQC2); scFv Fragment | ELISA | Mouse scFv |
| PSBC-132 | Mouse Anti-ITGA1 Recombinant Antibody (clone mAb6); scFv Fragment | ELISA | Mouse scFv |
| HPAB-1764-FY-F(E) | Human Anti-ITGA1 Recombinant Antibody (clone 3.40); scFv Fragment | ELISA, FuncS | Human scFv |
| HPAB-1765-FY-F(E) | Human Anti-ITGA1 Recombinant Antibody (clone 2.19); scFv Fragment | ELISA, FuncS | Human scFv |
| HPAB-1766-FY-F(E) | Human Anti-ITGA1 Recombinant Antibody (clone 7.22); scFv Fragment | ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-356CQ | Human Anti-ITGA1 Recombinant Antibody (TAB-356CQ) | ELISA, FC | Human IgG4, κ |
| TAB-357CQ | Human Anti-ITGA1 Recombinant Antibody (TAB-357CQ) | ELISA, FC | Human IgG4, κ |
| TAB-356CQ-S(P) | Human Anti-ITGA1 Recombinant Antibody; scFv Fragment (TAB-356CQ-S(P)) | ELISA, FC | Human scFv |
| TAB-357CQ-S(P) | Human Anti-ITGA1 Recombinant Antibody; scFv Fragment (TAB-357CQ-S(P)) | ELISA, FC | Human scFv |
| TAB-356CQ-F(E) | Human Anti-ITGA1 Recombinant Antibody; Fab Fragment (TAB-356CQ-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0292MZ | Chicken Anti-ITGA1 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-121 | Recombinant Mouse Anti-Integrin alpha 1 Antibody (AQC2) | WB, ELISA, Neut, FuncS | IgG |
| PABX-188 | Mouse Anti-ITGA1 Recombinant Antibody (PABX-188) | WB, ELISA, FuncS | IgG |
| PABX-121-F (E) | Recombinant Mouse Anti-Integrin alpha 1 Antibody Fab Fragment (AQC2) | WB, ELISA, Neut, FuncS | Fab |
| PABX-188-F (E) | Mouse Anti-ITGA1 Recombinant Antibody; Fab Fragment (PABX-188-F (E)) | WB, ELISA, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1541CQ | Recombinant Mouse Anti-ITGA1 Antibody (5E8D9) | Neut, ICC, IF | IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC383 | Recombinant Anti-ITGA1 Vesicular Antibody, EV Displayed (VS-0425-YC383) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3611 | Anti-ITGA1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3612 | Anti-Rat ITGA1 Immunohistochemistry Kit | IHC |
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