Human Anti-ITGA4 Recombinant Antibody (clone MAb 21.6) (CAT#: PABL-249)

Recombinant Human Antibody (MAb 21.6) is capable of binding to ITGA4, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-ITGA4 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-ITGA4 mAb and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
RNA Expression

Specifications

  • Immunogen
  • Human integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • Human IgG
  • Specificity
  • Human ITGA4
  • Species Reactivity
  • Human
  • Clone
  • MAb 21.6
  • Applications
  • Neut, FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • ITGA4; integrin; alpha 4 (antigen CD49D; alpha 4 subunit of VLA-4 receptor); IA4; CD49D; integrin alpha-4; 269C wild type; integrin alpha 4; integrin alpha-IV; VLA-4 subunit alpha; integrin alpha-4 subunit; CD49 antigen-like family member D; antigen CD49D; alpha-4 subunit of VLA-4 receptor; very late activation protein 4 receptor; alpha 4 subunit

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone MAb 21.6"

See other products for "ITGA4"

Humanized Antibody

CAT Product Name Application Type
TAB-135 Anti-Human Integrin alpha 4 beta 7 Recombinant Antibody (Etrolizumab) IF, IP, Neut, FuncS, ELISA, FC, ICC IgG1 - kappa

Immunotoxin

CAT Product Name Application Type
AGTO-L029G anti-ITGA4 immunotoxin 15A8 (IgG)-Gel Cytotoxicity assay, Functional assay

Human Antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1553CQ Recombinant Rat Anti-Itga4 Antibody (CBL914) FC, Neut IgG2a, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1873 Hi-Affi™ Recombinant Rabbit Anti-ITGA4 Monoclonal Antibody (DS1873AB) ICC/IF, IHC-P, IP, WB IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-135 Afuco™ Anti-ITGA4 ADCC Recombinant Antibody (Etrolizumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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