Anti-human ITGAE Fab Fragment (3G6 (IgG1)) (CAT#: TAB-745LC-F(E))
Recombinant monoclonal antibody 3G6 (IgG1) is a chimeric (mouse/human) monoclonal antibody that specifically binds to human alphaE integrin and can be potentially used in the treatment of inflammatory diseases.
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Normal Tissue
RNA Expression
Figure 1 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows distinct cytoplasmic positivity in intra-epithelial lymphocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36313/ihc_selected.jpg
(Immunohistochemical staining of human small intestine shows distinct cytoplasmic positivity in intra-epithelial lymphocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36313/ihc_selected.jpg
Figure 2 High expression in small intestine
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52147/168912_A_4_2_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52147/168912_A_4_2_selected.jpg
Figure 3 Low expression in cerebral cortex
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52147/168912_B_9_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52147/168912_B_9_5_val_selected.jpg
Figure 4 Colon
(Enterocytes - Mucosal lymphoid cells Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52147/168912_A_8_3.jpg
(Enterocytes - Mucosal lymphoid cells Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52147/168912_A_8_3.jpg
Figure 5 Kidney
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52147/168912_A_8_5.jpg
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52147/168912_A_8_5.jpg
Figure 6 RNA cell line category: Cell line enriched (MOLT-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000083457-ITGAE
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000083457-ITGAE
Specifications
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Chimeric antibody (mouse/human)
- Specificity
- Human
- Clone
- 3G6 (IgG1)
- Applications
- ELISA, FC
- Related Disease
- Inflammatory diseases
Target
- Alternative Names
- ITGAE; integrin; alpha E (antigen CD103; human mucosal lymphocyte antigen 1; alpha polypeptide); CD103; HUMINAE; integrin alpha-E; HML-1 antigen; integrin alpha-IEL; mucosal lymphocyte 1 antigen; antigen CD103; human mucosal lymphocyte antigen 1; alpha polypeptide; 3G6; Integrin, alpha E
- Gene ID
- 3682
- UniProt ID
- P38570
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1726z | Mouse Anti-ITGAE Recombinant Antibody (clone 23B3) | WB, FC, IHC, IP | Mouse IgG1, κ |
| FN-104CQ | Recombinant Rat Anti-ITGAE Antibody (M290) | IF, Neut, FC | Rat IgG2a |
| FAMAB-1581CQ | Mouse Anti-ITGAE Recombinant Antibody (clone OX62) | Depletion, IP, MACS, WB, FC, IF, IHC-Fr | Mouse IgG1 |
| ZG-0750F | Mouse Anti-ITGAE Recombinant Antibody (clone AX.14) | FC | Mouse IgG1 |
| VS3-CJ924 | Rabbit Anti-ITGAE Recombinant Antibody (VS3-CJ924) | IHC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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