Afuco™ Anti-Human ITGB2 ADCC Recombinant Antibody (MLN2201), ADCC Enhanced
CAT#: AFC-443CL
Anti-ITGB2 ADCC Enhanced Antibody (MLN2201) is an ADCC enhanced antibody produced by our Afuco™ platform. MLN2201 is a humanized monoclonal antibody being developed for conditions related to inflammation of the heart and blood vessels.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16894/202_B8_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line EFO-21
Immunofluorescent staining of human cell line EFO-21 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16894/131_C9_1_blue_red_green.jpg
Subcellular Location
Figure 3 IF staining of human cell line BJ
Immunofluorescent staining of human cell line U-4 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16894/1842_G1_63_blue_red_green.jpg
RNA Expression
Figure 4 RNA cell line category: Group enriched (THP-1, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160255-ITGB2
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Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Inflammatory Diseases
Product Property
- Purity
- >95% as determined by analysis by RP-HPLC
- Storage
- ≤1 year at -20°C.
Target
- Alternative Names
- ITGB2; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1; integrin beta-2; integrin beta chain, beta 2; complement receptor C3 beta-subunit; leukocyte cell adhesion molecule CD18; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; cell surface adhesion glycoprotein (LFA-1/CR3/P150, 959 beta subunit precursor)
- Gene ID
- 3689
- UniProt ID
- B4E0R1
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-044 | Anti-Human ITGB2 Recombinant Antibody (TAB-044) | Neut, ELISA, IF, IP, FuncS, FC, IHC | IgG4 |
| TAB-154-F(E) | Anti-Human CD18 Recombinant Antibody F(ab')2 Fragment (TAB-154-F(E)) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1 |
| TAB-461CL | Human Anti-ITGB2 Recombinant Antibody (TAB-461CL) | ELISA | Human IgG |
| TAB-1582CL | Anti-Human ITGB2 Recombinant Antibody (Hu23F2G (also known as LeukArrest and Rovelizumab)) | IP, FuncS | Humanized antibody |
| TAB-1582CL-S(P) | Anti-Human ITGB2 Recombinant Antibody scFv Fragment (Hu23F2G (also known as LeukArrest and Rovelizumab)) | Inhib | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1581CL | Anti-Human ITGB2 Recombinant Antibody (23F2G) | Inhib | |
| TAB-1581CL-S(P) | Anti-Human ITGB2 Recombinant Antibody scFv Fragment (23F2G) | Inhib | |
| TAB-1581CL-F(E) | Anti-Human ITGB2 Recombinant Antibody Fab Fragment (23F2G) | Inhib |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0298MZ | Chicken Anti-ITGB2 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1590CQ | Recombinant Mouse Anti-ITGB2 Antibody (MEM-48) | BL, FC, IHC-Fr, IHC-P, IP, WB | IgG1 |
| NEUT-1591CQ | Recombinant Mouse Anti-ITGB2 Antibody (TS1/18) | BL, FC, ICC, IF, IHC, WB | IgG1 |
| NEUT-1592CQ | Recombinant Mouse Anti-ITGB2 Antibody (YFC118.12) | FC, BL | IgG1, κ |
| NEUT-1593CQ | Recombinant Mouse Anti-ITGB2 Antibody (MEM-148) | FC, IP, WB, BL, FuncS | IgG1 |
| NEUT-1594CQ | Recombinant Hamster Anti-Itgb2 Antibody (2E6) | BL, ICC, IP, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1884 | Hi-Affi™ Recombinant Rabbit Anti-ITGB2 Monoclonal Antibody (DS1884AB) | IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0801-CN-S(P) | Recombinant Mouse Anti-ITGB2 Antibody scFv Fragment (CBCNC1) | ELISA, IHC | Mouse scFv |
| HPAB-1769-FY-F(E) | Human Anti-ITGB2 Recombinant Antibody (clone D2-57); scFv Fragment | ELISA | Human scFv |
| HPAB-1770-FY-F(E) | Human Anti-ITGB2 Recombinant Antibody (clone DX-2001); scFv Fragment | ELISA | Human scFv |
| HPAB-1376WJ-S(P) | Human Anti-ITGB2 Recombinant Antibody; scFv Fragment (clone huH52) | ELISA, WB | Human scFv |
| HPAB-1569WJ-S(P) | Mouse Anti-ITGB2 Recombinant Antibody; scFv Fragment (clone 1B4) | ELISA, WB, IF | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0801-CN-F(E) | Recombinant Mouse Anti-ITGB2 Antibody Fab Fragment (CBCNC1) | ELISA, IHC | Mouse Fab |
| HPAB-1769-FY-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone D2-57); Fab Fragment | ELISA | Human Fab |
| HPAB-1770-FY-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone DX-2001); Fab Fragment | ELISA | Human Fab |
| HPAB-1292WJ-F(E) | Rat Anti-ITGB2 Recombinant Antibody (clone YFC51.1); Fab Fragment | ELISA, FC | Rat Fab |
| HPAB-1293WJ-F(E) | Human Anti-ITGB2 Recombinant Antibody (clone LDP-01); Fab Fragment | ELISA, FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-044 | Afuco™ Anti-ITGB2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-044) | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FN-006CQ | Recombinant Mouse Anti-ITGB2 Antibody (IB4) | FC, Block | Mouse IgG2a |
| FN-007CQ | Mouse Anti-ITGB2 Recombinant Antibody (clone IB4) | FC, Block | Mouse F(ab')2 |
| HPAB-1769-FY | Human Anti-ITGB2 Recombinant Antibody (clone D2-57) | ELISA | Human IgG |
| HPAB-1770-FY | Human Anti-ITGB2 Recombinant Antibody (clone DX-2001) | ELISA | Human IgG |
| HPAB-1771-FY | Human Anti-ITGB2 Recombinant Antibody (clone C1-54) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY153 | CytoStream™ Mouse Anti-ITGB2 Recombinant Antibody (clone WT.3) | FC, Block, IHC, IP | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY138 | Human Anti-ITGB2 (clone Hu23F2G) scFv-Fc Chimera | Block, FC, IHC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC336 | Recombinant Anti-ITGB2 Vesicular Antibody, EV Displayed (VS-0425-YC336) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3657 | Anti-ITGB2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3658 | Anti-Mouse ITGB2 Immunohistochemistry Kit | IHC |
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