Anti-Human ITGB2 Recombinant Antibody scFv Fragment (Hu23F2G (also known as LeukArrest and Rovelizumab))
CAT#: TAB-1582CL-S(P)
This antibody immunologically reacts with the common β chain (CD18) of human leukocyte integrins and/or competes with mAb 60.3 for binding to human LFA-1, which is useful for the alleviation of symptoms associated with inflammatory disease states, and more particularly to the inhibition of inflammatory processes associated with the multiple sclerosis disease.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16894/202_B8_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line EFO-21
Immunofluorescent staining of human cell line EFO-21 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16894/131_C9_1_blue_red_green.jpg
Subcellular Location
Figure 3 IF staining of human cell line BJ
Immunofluorescent staining of human cell line U-4 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16894/1842_G1_63_blue_red_green.jpg
RNA Expression
Figure 4 RNA cell line category: Group enriched (THP-1, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160255-ITGB2
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Specifications
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- Humanized antibody
- Specificity
- Human
- Clone
- Hu23F2G (also known as LeukArrest and Rovelizumab)
- Related Disease
- Inflammatory disease
Target
- Alternative Names
- ITGB2; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1; integrin beta-2; integrin beta chain, beta 2; complement receptor C3 beta-subunit; leukocyte cell adhesion molecule CD18; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; cell surface adhesion glycoprotein (LFA-1/CR3/P150, 959 beta subunit precursor)
- Gene ID
- 3689
- UniProt ID
- B4E0R1
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone Hu23F2G (also known as LeukArrest and Rovelizumab)"
- CAT
- Product Name
- TAB-1582CL
- Anti-Human ITGB2 Recombinant Antibody (Hu23F2G (also known as LeukArrest and Rovelizumab))
See other products for "ITGB2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-980 | Recombinant Mouse Anti-Human ITGB2 Antibody F(ab')2 Fragment, clone IB4 | FC, Inhib | F(ab')2 |
| FAMAB-0203CQ-F(E) | Mouse Anti-ITGB2 Recombinant Antibody (clone 60.3); Fab Fragment | ELISA, WB, Block | Mouse Fab |
| FAMAB-0204CQ-F(E) | Human Anti-ITGB2 Recombinant Antibody (clone h60.3); Fab Fragment | ELISA, WB, Block | Human Fab |
| HPAB-1874-FY-S(P) | Human Anti-ITGB2 Recombinant Antibody (clone NA-8); Fab Fragment | Block | Humanized Fab |
| HPAB-1376WJ-F(E) | Human Anti-ITGB2 Recombinant Antibody; Fab Fragment (clone huH52) | ELISA, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-099 | Recombinant Anti-Human ITGB2 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-044 | Anti-Human ITGB2 Recombinant Antibody (TAB-044) | Neut, ELISA, IF, IP, FuncS, FC, IHC | IgG4 |
| TAB-154-F(E) | Anti-Human CD18 Recombinant Antibody F(ab')2 Fragment (TAB-154-F(E)) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1 |
| TAB-461CL | Human Anti-ITGB2 Recombinant Antibody (TAB-461CL) | ELISA | Human IgG |
| TAB-1582CL | Anti-Human ITGB2 Recombinant Antibody (Hu23F2G (also known as LeukArrest and Rovelizumab)) | IP, FuncS | Humanized antibody |
| TAB-1582CL-F(E) | Anti-Human ITGB2 Recombinant Antibody Fab Fragment (Hu23F2G (also known as LeukArrest and Rovelizumab)) | Inhib | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1581CL | Anti-Human ITGB2 Recombinant Antibody (23F2G) | Inhib | |
| TAB-1581CL-S(P) | Anti-Human ITGB2 Recombinant Antibody scFv Fragment (23F2G) | Inhib | |
| TAB-1581CL-F(E) | Anti-Human ITGB2 Recombinant Antibody Fab Fragment (23F2G) | Inhib |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0298MZ | Chicken Anti-ITGB2 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1590CQ | Recombinant Mouse Anti-ITGB2 Antibody (MEM-48) | BL, FC, IHC-Fr, IHC-P, IP, WB | IgG1 |
| NEUT-1591CQ | Recombinant Mouse Anti-ITGB2 Antibody (TS1/18) | BL, FC, ICC, IF, IHC, WB | IgG1 |
| NEUT-1592CQ | Recombinant Mouse Anti-ITGB2 Antibody (YFC118.12) | FC, BL | IgG1, κ |
| NEUT-1593CQ | Recombinant Mouse Anti-ITGB2 Antibody (MEM-148) | FC, IP, WB, BL, FuncS | IgG1 |
| NEUT-1594CQ | Recombinant Hamster Anti-Itgb2 Antibody (2E6) | BL, ICC, IP, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1884 | Hi-Affi™ Recombinant Rabbit Anti-ITGB2 Monoclonal Antibody (DS1884AB) | IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0801-CN-S(P) | Recombinant Mouse Anti-ITGB2 Antibody scFv Fragment (CBCNC1) | ELISA, IHC | Mouse scFv |
| HPAB-1769-FY-F(E) | Human Anti-ITGB2 Recombinant Antibody (clone D2-57); scFv Fragment | ELISA | Human scFv |
| HPAB-1770-FY-F(E) | Human Anti-ITGB2 Recombinant Antibody (clone DX-2001); scFv Fragment | ELISA | Human scFv |
| HPAB-1771-FY-F(E) | Human Anti-ITGB2 Recombinant Antibody (clone C1-54); scFv Fragment | ELISA | Human scFv |
| HPAB-1874-FY-F(E) | Human Anti-ITGB2 Recombinant Antibody (clone NA-8); scFv Fragment | Block | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0283-CN | Recombinant Rabbit Anti-ITGB2 Monoclonal Antibody (JM71-31) | WB, IP | Rabbit IgG |
| FN-085CQ | Recombinant Rat Anti-ITGB2 Antibody (C71/16) | IHC-Fr, FC, IP, FuncS | Rat IgG2a |
| HPAB-1207WJ | Human Anti-ITGB2 Recombinant Antibody (clone pxCD18-7T3) | ELISA | Human IgG |
| HPAB-1292WJ | Rat Anti-ITGB2 Recombinant Antibody (clone YFC51.1) | ELISA, FC | Rat IgG |
| HPAB-1293WJ | Human Anti-ITGB2 Recombinant Antibody (clone LDP-01) | ELISA, FC | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-044 | Afuco™ Anti-ITGB2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-044) | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY153 | CytoStream™ Mouse Anti-ITGB2 Recombinant Antibody (clone WT.3) | FC, Block, IHC, IP | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY138 | Human Anti-ITGB2 (clone Hu23F2G) scFv-Fc Chimera | Block, FC, IHC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC336 | Recombinant Anti-ITGB2 Vesicular Antibody, EV Displayed (VS-0425-YC336) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3657 | Anti-ITGB2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3658 | Anti-Mouse ITGB2 Immunohistochemistry Kit | IHC |
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