Human Anti-IL31RA Recombinant Antibody (CAT#: TAB-427CL)
Recombinant Humanized monoclonal antibody expressed in CHO binding to Human and Monkey IL31RA. The anti-IL31RA antibodiess having an effective neutralizing activity against IL31RA are useful as pharmaceuticals for treating or preventing inflammatory diseases.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51532/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51532/if_selected.jpg
Figure 2 IHC staining of human lung
(Immunohistochemical staining of human lung shows moderate cytoplasmic positivity in macrophages.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68114/160946_A_3_4_selected.jpg
(Immunohistochemical staining of human lung shows moderate cytoplasmic positivity in macrophages.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68114/160946_A_3_4_selected.jpg
Figure 3 IF staining of human cell line PC-3
(Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51532/986_C6_2_red_green.jpg
(Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51532/986_C6_2_red_green.jpg
Figure 4 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51532/832_C6_4_red_green.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51532/832_C6_4_red_green.jpg
Figure 5 Lymph node
(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68114/160946_A_9_8.jpg
(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68114/160946_A_9_8.jpg
Figure 6 RNA cell line category: Cell line enhanced (GAMG, HBEC3-KT, HHSteC, hTERT-HME1, U-2 OS, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164509-IL31RA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164509-IL31RA
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Antibody
- Species Reactivity
- Human, Monkey
- Related Disease
- Inflammatory Diseases
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- CRL; GPL; CRL3; GLMR; GLM-R; PLCA2; hGLM-R; IL-31RA; PRO21384; zcytoR17
- Gene ID
- 133396
- UniProt ID
- Q8NI17
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-439CQ | Anti-Human IL31RA Recombinant Antibody (TAB-439CQ) | ELISA, IHC, FC, IP, IF, FuncS | IgG2, κ |
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