Afuco™ Anti-Human LAMP1 ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-462CL
Anti-LAMP1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibodies which specifically bind human and Macaca fascicularis lysosomal-associated membrane protein 1 (LAMP1) proteins are used for treating cancer in a patient harboring LAMP1 gene copy number gain in cancer cells.
Gene Expression
Normal Tissue
Figure 1 Ihc staining of human urinary bladder
Immunohistochemical staining of human urinary bladder shows strong granular positivity in urothelial cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/14750/34136_A_5_5_selected.jpg
Normal Tissue
Figure 2 IHC staining of human colon
Immunohistochemical staining of human colon shows strong cytoplasmic positivity(granular pattern) in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Glial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_B_9_5.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_8_4.jpg
Normal Tissue
Figure 5 Pancreas
Exocrine glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_1_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_7_5.jpg
Normal Tissue
Figure 7 Testis
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_6_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000185896-LAMP1
❮
❯
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
- Storage
- Store at -20°C. Open under aseptic conditions.
Target
- Alternative Names
- LAMP1; lysosomal-associated membrane protein 1; LAMPA; CD107a; LGP120; lysosome-associated membrane glycoprotein 1; LAMP-1; CD107 antigen-like family member A; lysosome-associated membrane protein 1
- Gene ID
- 3916
- UniProt ID
- A0A024RDY3
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for AFC-462CL. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "LAMP1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-611-F(E) | Recombinant Anti-human LAMP1 Antibody Fab Fragment | IF, FuncS | Fab |
| MHH-611-F(E) | Recombinant Human Anti-human LAMP1 Antibody Fab Fragment | WB, Neut, FuncS | Fab |
| HPAB-0035-LSX-F(E) | Human Anti-LAMP1 Recombinant Antibody; Fab Fragment (HPAB-0035-LSX-F(E)) | ELISA, IHC | Chimeric (mouse/human) Fab |
| HPAB-0036-LSX-F(E) | Human Anti-LAMP1 Recombinant Antibody; Fab Fragment (HPAB-0036-LSX-F(E)) | ELISA, IHC | Chimeric (mouse/human) Fab |
| HPAB-0037-LSX-F(E) | Human Anti-LAMP1 Recombinant Antibody; Fab Fragment (HPAB-0037-LSX-F(E)) | ELISA, IHC | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-611-S(P) | Recombinant Anti-human LAMP1 Antibody scFv Fragment | IP, IF, Biosensors, FuncS | scFv |
| MHH-611-S(P) | Recombinant Human Anti-human LAMP1 Antibody scFv Fragment | ELISA, WB, FC, FuncS | scFv |
| HPAB-0035-LSX-S(P) | Human Anti-LAMP1 Recombinant Antibody; scFv Fragment (HPAB-0035-LSX-S(P)) | ELISA, IHC | Human scFv |
| HPAB-0036-LSX-S(P) | Human Anti-LAMP1 Recombinant Antibody; scFv Fragment (HPAB-0036-LSX-S(P)) | ELISA, IHC | Human scFv |
| HPAB-0037-LSX-S(P) | Mouse Anti-LAMP1 Recombinant Antibody; scFv Fragment (HPAB-0037-LSX-S(P)) | ELISA, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2010 | Hi-Affi™ Recombinant Rabbit Anti-LAMP1 Monoclonal Antibody (DS2010AB) | WB, IHC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0035-LSX | Human Anti-LAMP1 Recombinant Antibody (HPAB-0035-LSX) | ELISA, IHC, ADCC | Human IgG |
| HPAB-0036-LSX | Human Anti-LAMP1 Recombinant Antibody (HPAB-0036-LSX) | ELISA, IHC, ADCC, FuncS | Human IgG |
| HPAB-0037-LSX | Human Anti-LAMP1 Recombinant Antibody (HPAB-0037-LSX) | ELISA, IHC | Chimeric (mouse/human) IgG |
| HPAB-0038-LSX | Human Anti-LAMP1 Recombinant Antibody (HPAB-0038-LSX) | ELISA, IHC, FC, ADCC, FuncS | Human IgG |
| HPAB-0039-LSX | Human Anti-LAMP1 Recombinant Antibody (HPAB-0039-LSX) | ELISA, IHC | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC849 | AbPlus™ Anti-LAMP1 Magnetic Beads (VS-0724-YC849) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY301 | Mouse Anti-NHP LAMP1 Recombinant Antibody (clone H4A3) | WB, IHC, FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC666 | Recombinant Anti-LAMP1 Vesicular Antibody, EV Displayed (VS-0425-YC666) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3937 | Anti-LAMP1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3938 | Anti-Mouse LAMP1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3939 | Anti-Human LAMP1 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
-2.png)
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, Activ, Block
Application: ELISA, FC, FuncS
Application: EM, ELISA, ICC, IHC-Fr, IHC-P, WB
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
