Human Anti-LAMP1 Recombinant Antibody (HPAB-0037-LSX) (CAT#: HPAB-0037-LSX)
This antibody specifically binds human and Macaca fascicularis lysosomal-associated membrane protein 1 (LAMP1). LAMP1, also known as CD107 antigen-like family member A (CD107a), is highly expressed in late endosomes and lysosomes. This antibody is a chimeric (mouse/human) monoclonal antibody that could induce an anti-tumor activity in vivo in a murine model.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Ihc staining of human urinary bladder
(Immunohistochemical staining of human urinary bladder shows strong granular positivity in urothelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14750/34136_A_5_5_selected.jpg
(Immunohistochemical staining of human urinary bladder shows strong granular positivity in urothelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14750/34136_A_5_5_selected.jpg
Figure 2 IHC staining of human colon
(Immunohistochemical staining of human colon shows strong cytoplasmic positivity(granular pattern) in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/ihc_selected.jpg
(Immunohistochemical staining of human colon shows strong cytoplasmic positivity(granular pattern) in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/ihc_selected.jpg
Figure 3 Cerebral cortex
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Glial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_B_9_5.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Glial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_B_9_5.jpg
Figure 4 Liver
(Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_8_4.jpg
(Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_8_4.jpg
Figure 5 Pancreas
(Exocrine glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_1_3.jpg
(Exocrine glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_1_3.jpg
Figure 6 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_7_5.jpg
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_7_5.jpg
Figure 7 Testis
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_6_6.jpg
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_6_6.jpg
Figure 8 Lymph node
(Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_8_8.jpg
(Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4260/19501_A_8_8.jpg
Figure 9 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000185896-LAMP1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000185896-LAMP1
Specifications
- Immunogen
- CR-LRB-010P
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Chimeric (mouse/human) IgG
- Specificity
- Human LAMP1
- Species Reactivity
- Human, Macaca fascicularis
- Applications
- ELISA, IHC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-611 | Recombinant Human Anti-human LAMP1 Antibody | WB, IF, FuncS | IgG |
| MOB-1060CT | Recombinant Mouse anti-Human LAMP1 Monoclonal antibody (C-U58) | FC | |
| HPAB-0035-LSX | Human Anti-LAMP1 Recombinant Antibody (HPAB-0035-LSX) | ELISA, IHC, ADCC | Human IgG |
| HPAB-0036-LSX | Human Anti-LAMP1 Recombinant Antibody (HPAB-0036-LSX) | ELISA, IHC, ADCC, FuncS | Human IgG |
| HPAB-0038-LSX | Human Anti-LAMP1 Recombinant Antibody (HPAB-0038-LSX) | ELISA, IHC, FC, ADCC, FuncS | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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