Afuco™ Anti-Human LILRA4 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-471CL)
Anti-LILRA4 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. Anti-ILT7 antibody binds to plasmacytoid dendritic cells (pDCs), a subset of dendritic cells (DCs). pDCs is known as a major source of IFNα; overproduction of IFNα is considered to be one of the major causes of autoimmune diseases. Anti-ILT7 antibody specifically recognizes and kills pDCs to suppress the IFNα supply, which leads to the improvement of autoimmune disease symptoms.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
Figure 1 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_8_selected.jpg
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_8_selected.jpg
Figure 2 Colon
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_3.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_3.jpg
Figure 3 Kidney
(Cells in glomeruli
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_5.jpg
(Cells in glomeruli
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_5.jpg
Figure 4 Testis
(Elongated or late spermatids
Staining: High
Intensity: Strong
Quantity:>75%
Round or early spermatids
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_5_6.jpg
(Elongated or late spermatids
Staining: High
Intensity: Strong
Quantity:>75%
Round or early spermatids
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_5_6.jpg
Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Autoimmune Diseases
Product Property
- Purity
- >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- LILRA4; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4; ILT7; CD85g; leukocyte immunoglobulin-like receptor subfamily A member 4; immunoglobulin-like transcript 7; CD85 antigen-like family member G; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 4
- Gene ID
- 23547
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1095CT | Recombinant Mouse anti-Human LILRA4 Monoclonal antibody (28H20.3) | FC | |
| FN-194CQ | Recombinant Mouse Anti-LILRA4 Antibody (17G10.2) | FC, FuncS, IP | Mouse IgG1 |
| HPAB-N0168-YC | Human Anti-LILRA4 Recombinant Antibody (HPAB-N0168-YC) | FC, ELISA, FuncS | Humanized IgG1 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0168-YC-S(P) | Human Anti-LILRA4 Recombinant Antibody; scFv Fragment (HPAB-N0168-YC-S(P)) | FC, ELISA, FuncS | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0168-YC-F(E) | Human Anti-LILRA4 Recombinant Antibody; Fab Fragment (HPAB-N0168-YC-F(E)) | FC, ELISA, FuncS | Humanized Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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