Human Anti-LPA Recombinant Antibody (clone hB3); Fab Fragment (CAT#: HPAB-0255-YC-F(E))
LPA is a bioactive lipid mediating multiple cellular responses including proliferation, differentiation, angiogenesis, motility, and protection from apoptosis in a variety of cell types. This antibody Fab fragment (hB3) against LPA is a humanized antibody Fab fragment derived from mouse antibody B3.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IHC staining of human liver
(Immunohistochemical staining of human liver shows moderate cytoplasmic and membranous positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_8_4_selected.jpg
(Immunohistochemical staining of human liver shows moderate cytoplasmic and membranous positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_8_4_selected.jpg
Figure 2 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows distinc extra cellular and some, weaker membranous and cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16072/ihc_selected.jpg
(Immunohistochemical staining of human kidney shows distinc extra cellular and some, weaker membranous and cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16072/ihc_selected.jpg
Figure 3 Cerebral cortex
(Endothelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_B_7_5.jpg
(Endothelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_B_7_5.jpg
Figure 4 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_9_3.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_9_3.jpg
Figure 5 Testis
(Leydig cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_4_6.jpg
(Leydig cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_4_6.jpg
Figure 6 Skin
(Epidermal cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_B_6_8.jpg
(Epidermal cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_B_6_8.jpg
Figure 7 Lymph node
(Germinal center cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16072/36402_A_9_8.jpg
(Germinal center cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16072/36402_A_9_8.jpg
Figure 8 RNA cell line category: Cell line enriched (RT4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198670-LPA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198670-LPA
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized Fab
- Specificity
- Human LPA
- Species Reactivity
- Human
- Clone
- hB3
- Applications
- ELISA, FuncS
- Related Disease
- Fibrosis, Ocular disease
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone hB3"
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-329 | Recombinant Human Anti-S. aureus LPA Antibody | WB, ELISA, FuncS | IgG |
| MOB-1248MZ | Recombinant Mouse Anti-Human LPA Antibody (clone 9G7B0,9I6D6) | ELISA, IHC-P, WB | Mouse antibody |
| HPAB-0253-YC | Mouse Anti-LPA Recombinant Antibody (clone 2D1) | ELISA, WB | Mouse IgG |
| HPAB-0254-YC | Mouse Anti-LPA Recombinant Antibody (clone B3) | ELISA, FuncS | Mouse IgG |
| HPAB-1295-FY | Human Anti-LPA Recombinant Antibody (clone B7) | ELISA, Inhib | Humanized IgG1, κ |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-329 | Recombinant Human Anti-S. aureus LPA Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
| HPAB-0253-YC-F(E) | Mouse Anti-LPA Recombinant Antibody (clone 2D1); Fab Fragment | ELISA, WB | Mouse Fab |
| HPAB-0775-WJ-F(E) | Mouse Anti-LPA Recombinant Antibody (clone B58); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0776-WJ-F(E) | Mouse Anti-LPA Recombinant Antibody (clone A63); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0777-WJ-F(E) | Mouse Anti-LPA Recombinant Antibody (clone 3A6); Fab Fragment | ELISA | Mouse Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0340CL | Anti-LPA Recombinant Antibody (LT3015 [B7(LT3000, Lpathomab)]) | ELISA, SPR, Inhib, FuncS | Humanized Antibody |
| TAB-0340CL-S(P) | Anti-LPA Recombinant Antibody scFv Fragment (LT3015 [B7(LT3000, Lpathomab)]) | ELISA, SPR, Inhib, FuncS | Humanized Antibody |
| TAB-0340CL-F(E) | Anti-LPA Recombinant Antibody Fab Fragment (LT3015 [B7(LT3000, Lpathomab)]) | ELISA, SPR, Inhib, FuncS | Humanized Antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2076 | Hi-Affi™ Recombinant Rabbit Anti-LPA Monoclonal Antibody (DS2076AB) | WB, IHC | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0253-YC-S(P) | Mouse Anti-LPA Recombinant Antibody (clone 2D1); scFv Fragment | ELISA, WB | Mouse scFv |
| HPAB-0254-YC-S(P) | Mouse Anti-LPA Recombinant Antibody (clone B3); scFv Fragment | ELISA, FuncS | Mouse scFv |
| HPAB-0255-YC-S(P) | Human Anti-LPA Recombinant Antibody (clone hB3); scFv Fragment | ELISA, FuncS | Humanized scFv |
| HPAB-1295-FY-F(E) | Human Anti-LPA Recombinant Antibody (clone B7); scFv Fragment | ELISA | Humanized scFv |
| HPAB-0775-WJ-S(P) | Mouse Anti-LPA Recombinant Antibody (clone B58); scFv Fragment | ELISA | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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