Mouse Anti-LPA Recombinant Antibody (clone B3); Fab Fragment (CAT#: HPAB-0254-YC-F(E))
This mouse antibody Fab fragment specifically reacts to LPA. The anti-LPA antibody is able to reduce the production of pro-growth factor IL-8 in vitro.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IHC staining of human liver
(Immunohistochemical staining of human liver shows moderate cytoplasmic and membranous positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_8_4_selected.jpg
(Immunohistochemical staining of human liver shows moderate cytoplasmic and membranous positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_8_4_selected.jpg
Figure 2 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows distinc extra cellular and some, weaker membranous and cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16072/ihc_selected.jpg
(Immunohistochemical staining of human kidney shows distinc extra cellular and some, weaker membranous and cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16072/ihc_selected.jpg
Figure 3 Cerebral cortex
(Endothelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_B_7_5.jpg
(Endothelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_B_7_5.jpg
Figure 4 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_9_3.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_9_3.jpg
Figure 5 Testis
(Leydig cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_4_6.jpg
(Leydig cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_4_6.jpg
Figure 6 Skin
(Epidermal cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_B_6_8.jpg
(Epidermal cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_B_6_8.jpg
Figure 7 Lymph node
(Germinal center cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16072/36402_A_9_8.jpg
(Germinal center cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16072/36402_A_9_8.jpg
Figure 8 RNA cell line category: Cell line enriched (RT4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198670-LPA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198670-LPA
Specifications
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human LPA
- Species Reactivity
- Human
- Clone
- B3
- Applications
- ELISA, FuncS
- Related Disease
- Fibrosis, Ocular disease
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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