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    Anti-Human LY75 Recombinant Antibody (CAT#: TAB-507CL)

    Recombinant Human monoclonal antibody expressed in CHO binding to Human LY75. The monoclonal antibodiess which bind to human DEC-205 can be used in a variety of dendritic cell-targeted therapies, for example, to enhance antigen presentation and/or induce T cell responses, such as cytotoxic T cell (CTL) responses, against a variety of target cells or pathogens, or to treat antigen presenting cell (APC)-mediated diseases.

    Specific Inquiry
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    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line
    Figure 1 IF staining of human cell line
    (Immunofluorescent staining of human cell line CACO-2 shows localization to the Golgi apparatus.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/54073/if_selected.jpg
    Figure 2 IHC staining of human colon
    Figure 2 IHC staining of human colon
    (Immunohistochemical staining of human colon shows moderate cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/49108/ihc_selected.jpg
    Normal Tissue
    Figure 3 IHC staining of human spleen
    Figure 3 IHC staining of human spleen
    (High expression. RNA expression: 18.4 nTPM)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1450/ihc_selected.jpg
    Figure 4 IHC staining of human skeletal muscle
    Figure 4 IHC staining of human skeletal muscle
    (Low expression. RNA expression: 0.3 nTPM)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1450/4611_B_3_6_val_selected.jpg
    Figure 5 Cerebral cortex
    Figure 5 Cerebral cortex
    (Neuropil
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/49108/127068_B_8_5.jpg
    Figure 6 Liver
    Figure 6 Liver
    (Cholangiocytes
    Staining: Low
    Intensity: Weak
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1450/4611_A_9_4.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Cells in glomeruli
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Cells in tubules
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/49108/127068_A_8_5.jpg
    Figure 8 Testis
    Figure 8 Testis
    (Elongated or late spermatids
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Leydig cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/49108/127068_A_5_6.jpg
    Figure 9 Lymph node
    Figure 9 Lymph node
    (Germinal center cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1450/4611_A_7_8.jpg
    RNA Expression
    Figure 10 RNA cell line category: Cell line enhanced (CAPAN-2, HDLM-2, Karpas-707, RT4, THP-1)
    Figure 10 RNA cell line category: Cell line enhanced (CAPAN-2, HDLM-2, Karpas-707, RT4, THP-1)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000054219-LY75

    Specifications

    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • Antibody
    • Species Reactivity
    • Human
    • Related Disease
    • APC-mediated Diseases

    Product Property

    • Purity
    • >97%, by SDS-PAGE under reducing conditions
    • Storage
    • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

    Target

    • Alternative Names
    • LY75; lymphocyte antigen 75; CD205; LY-75; CLEC13B; DEC-205; GP200-MR6; C-type lectin domain family 13 member B

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "LY75"

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    CAT Product Name Application Type
    MOB-637-F(E) Recombinant Anti-human LY75 Antibody Fab Fragment Neut, WB, FuncS Fab
    MHH-637-F(E) Recombinant Human Anti-human LY75 Antibody Fab Fragment ELISA, WB, IP, FuncS Fab
    HPAB-0470-YJ-F(E) Mouse Anti-LY75 Recombinant Antibody; Fab Fragment (HPAB-0470-YJ-F(E)) ELISA, IP, FuncS Mouse Fab
    HPAB-0471-YJ-F(E) Mouse Anti-LY75 Recombinant Antibody; Fab Fragment (HPAB-0471-YJ-F(E)) ELISA, IP, FuncS Mouse Fab
    HPAB-0661-YJ-F(E) Mouse Anti-LY75 Recombinant Antibody (clone CBL70YJ); Fab Fragment ELISA, IF Mouse Fab

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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