Anti-Human MEF2C Recombinant Antibody (CAT#: TAB-520CL)
Recombinant Human monoclonal antibody expressed in CHO binding to Human MEF2C. The antibodiess that bind selectively to MEF2C (Myocyte-specific enhancer factor 2C)-also known as MADS box transcription enhancer factor 2, polypeptide C, are used for cardiovascular diseases. MEF2C is one of several biomarkers expressed in committed cells differentiated from stem cells. MEF2C is a transcription factor in the MEF2 family of proteins, which play a role in cardiac morphogenesis, myogenesis and also vascular development.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line RH-30
(Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5533/if_selected.jpg
(Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5533/if_selected.jpg
Figure 2 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68196/152018_A_8_5.jpg
(Cells in glomeruli Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68196/152018_A_8_5.jpg
Figure 3 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Peritubular cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68196/152018_A_6_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Peritubular cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68196/152018_A_6_6.jpg
Figure 4 Skeletal muscle
(Myocytes Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68196/152018_B_2_6.jpg
(Myocytes Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68196/152018_B_2_6.jpg
Figure 5 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68196/152018_A_7_8.jpg
(Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68196/152018_A_7_8.jpg
Figure 6 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68196/152018_B_9_5.jpg
(Endothelial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68196/152018_B_9_5.jpg
Figure 7 Colon
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Enterocytes - Mucosal lymphoid cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68196/152018_A_7_3.jpg
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Enterocytes - Mucosal lymphoid cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68196/152018_A_7_3.jpg
Figure 8 RNA cell line category: Cell line enhanced (Daudi, HEL, Karpas-707, REH, WM-115)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000081189-MEF2C
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000081189-MEF2C
Specifications
- Host Species
- Human
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- Cardiovascular Diseases
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C
Target
- Alternative Names
- MEF2C; myocyte enhancer factor 2C; DEL5q14.3; C5DELq14.3; myocyte-specific enhancer factor 2C; MADS box transcription enhancer factor 2, polypeptide C
- Gene ID
- 4208
- UniProt ID
- Q06413
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Mouse Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1921z | Mouse Anti-MEF2C Recombinant Antibody (clone 21G4) | WB, FC, ICC, IF, IHC | Mouse IgG2a |
| VS3-WK130 | Mouse Anti-MEF2C Recombinant Antibody (clone G2-H2) | WB, ELISA | Mouse IgG1 |
| VS3-XY1059 | Mouse Anti-MEF2C Recombinant Antibody (clone 6H2G2) | ELISA, WB, IHC, FC | Mouse IgG1 |
| VS3-XY3427 | Rabbit Anti-MEF2C Recombinant Antibody (clone R07-6W9) | WB, IHC-P | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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