Anti-Human MET Recombinant Antibody Fab Fragment (PGIA-5A1)

Name: Anti-Human MET Recombinant Antibody Fab Fragment (PGIA-5A1)
SKU: TAB-040MZ-F(E)
Rating: 5 (1 reviews)

CAT#: TAB-040MZ-F(E)

This antibody is specific for c-Met, a protein tyrosine kinase whose ligand is hepatocyte growth factor (HGF). The antibody may block binding of HGF to c-Met and substantially inhibit c-Met activation.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/55607/if_selected.jpg

Subcellular Location Figure 2 IF staining of human cell line A-431

Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5282/if_selected.jpg

Subcellular Location Figure 3 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18577/if_selected.jpg

Normal Tissue Figure 4 Kidney

Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5282/15802_A_7_5.jpg

Normal Tissue Figure 5 Testis

Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5282/15802_A_6_6.jpg

RNA Expression Figure 6 RNA cell line category: Cell line enhanced (A-431, CAPAN-2)

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105976-MET

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Specifications

Host Species
Human

Derivation
Phagemid library

Type
Human antibody

Specificity
Human

Clone
PGIA-5A1

Applications
Western Blot, Enzyme-linked Immunosorbent Assay

Related Disease
Cancer, pathological liver conditions, and ophthalmic diseases

Target

Alternative Names
MET; MET proto-oncogene, receptor tyrosine kinase; HGFR; AUTS9; RCCP2; c-Met; hepatocyte growth factor receptor; SF receptor; HGF receptor; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyrosine kinase

Gene ID
4233

UniProt ID
A0A024R759

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Related Diseases

EGFR Tyrosine Kinase Inhibitor Resistance

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-040MZ-F(E).pdf

MSDS

MSDS - TAB-040MZ-F(E).pdf

COA

Certificate of Analysis Lookup

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CAT
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TAB-536LC	Human Anti-MET Recombinant Antibody (TAB-536LC)	Inhib	Human IgG2
TAB-537LC	Human Anti-MET Recombinant Antibody (TAB-537LC)	Inhib	Human IgG2
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HPAB-1301LY	Human Anti-MET Recombinant Antibody (HPAB-1301LY)	ELISA, IP	Human IgG2
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CAT	Product Name	Application	Type
HPAB-1298LY-F(E)	Human Anti-MET Recombinant Antibody; Fab Fragment (HPAB-1298LY-F(E))	ELISA, IP	Human Fab
HPAB-1299LY-F(E)	Human Anti-MET Recombinant Antibody; Fab Fragment (HPAB-1299LY-F(E))	ELISA, IP	Human Fab
HPAB-1300LY-F(E)	Human Anti-MET Recombinant Antibody; Fab Fragment (HPAB-1300LY-F(E))	ELISA, IP	Human Fab
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