Human Anti-MET Recombinant Antibody (clone 5D5); Fab Fragment (CAT#: PFBL-271)

Recombinant Human Antibody (5D5) is capable of binding to MET, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-MET fab and CH1-3 region of human fab and a light chain (LC) encoding VL from anti-MET fab and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody potently inhibits HGF binding and receptor phosphorylation and signaling and has antibody-like pharmacokinetics and antitumor activity.

Specific Inquiry Online Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • Human Fab
  • Specificity
  • Human MET
  • Species Reactivity
  • Human
  • Clone
  • 5D5
  • Applications
  • WB, Block, FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • MET; MET proto-oncogene; receptor tyrosine kinase; HGFR; AUTS9; RCCP2; c-Met; hepatocyte growth factor receptor; SF receptor; HGF receptor; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyrosine kinase

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 5D5"

See other products for "MET"

Humanized Antibody

CAT Product Name Application Type
TAB-190-F(E) Anti-Human Met(Onartuzumab) IP, IF, FuncS, FC, Neut, ELISA, ICC Fab / Fc - G1 - kappa
TAB-0332CL-F(E) Human Anti-MET Recombinant Antibody; Fab Fragment (TAB-0332CL-F(E)) ELISA Humanized Fab
TAB-0881CLV Human Anti-MET Recombinant Antibody (TAB-0881CLV) ELISA, FuncS Humanized IgG1
TAB-0883CLV Human Anti-MET Recombinant Antibody (TAB-0883CLV) ELISA, FuncS Humanized IgG1
TAB-0884CLV Human Anti-MET Recombinant Antibody (TAB-0884CLV) ELISA, FuncS Humanized IgG1

Immunotoxin

CAT Product Name Application Type
AGTO-G049E Anti-MET immunotoxin (Fab)-PE Cytotoxicity assay, Function study

Recombinant Antibody

CAT Product Name Application Type
PABL-271 Human Anti-MET Recombinant Antibody (clone 5D5) WB, Block, FuncS Human IgG
HPAB-0760-CN Mouse Anti-MET Recombinant Antibody (HPAB-0760-CN) WB, ELISA, IHC, IP Mouse IgG
HPAB-0761-CN Human Anti-MET Recombinant Antibody (HPAB-0761-CN) WB, ELISA, IHC, IP Chimeric (mouse/human) IgG1, κ
HPAB-0762-CN Human Anti-MET Recombinant Antibody (HPAB-0762-CN) WB, ELISA, IHC, IP Humanized IgG1, κ
HPAB-0030-WJ Human Anti-MET Recombinant Antibody (HPAB-0030-WJ) ELISA, WB Human IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
PABZ-155 Afuco™ Anti-MET ADCC Recombinant Antibody (Onartuzumab), ADCC Enhanced ELISA, Neut ADCC enhanced antibody
AFC-TAB-H24 Afuco™ Anti-MET ADCC Recombinant Antibody (Emibetuzumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody

Chimeric Antibody

CAT Product Name Application Type
TAB-002MZ Anti-Human MET Recombinant Antibody (MvDN30) IHC, PET imaging Chimeric antibody (mouse/human)
TAB-002MZ-F(E) Anti-Human MET Recombinant Antibody Fab Fragment (MvDN30) IHC, PET imaging Chimeric antibody (mouse/human)
TAB-0880CLV Human Anti-MET Recombinant Antibody (TAB-0880CLV) ELISA, FuncS Chimeric (mouse/human) IgG1
TAB-0880CLV-F(E) Human Anti-MET Recombinant Antibody; Fab Fragment (TAB-0880CLV-F(E)) ELISA, FuncS Chimeric (mouse/human) Fab
TAB-0880CLV-S(P) Mouse Anti-MET Recombinant Antibody; scFv Fragment (TAB-0880CLV-S(P)) ELISA, FuncS Mouse scFv

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1726CQ Recombinant Rabbit Anti-MET Antibody (CBL1008) Neut IgG

MHC Tetramer for Cancer

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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