Recombinant Humanized monoclonal antibody expressed in CHO binding to Human MET. This antibody is an anti-c-Met antibody with significant preclinical single-agent activity against MA human xenograft tumors. This antibody was well tolerated and appeared to have substantial single-agent activity. In this small cohort of gastric patients MA appears to be more common in treatment-refractory tumors than in primary untreated tumors, suggesting that screening efforts should focus on this treatment-refractory patient population.
Figure 1 Anti-Human MET Recombinant Antibody (TAB-521CL) in ELISA
ELISA analysis of TAB-521CL was performed by coating with Recombinant Human MET Protein.
Figure 2 Anti-Human MET Recombinant Antibody (TAB-521CL) in WB
Western blot analysis of TAB-521CL was performed with Recombinant Human MET Protein
Lane 1: Non-Reducing Antigen (0.5μg)
Lane 2: Reducing Antigen (0.5μg)
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G049E | Anti-MET immunotoxin (Fab)-PE | Cytotoxicity assay, Function study |
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(Creative Biolabs Cat# TAB-521CL, RRID: AB_3111967)
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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