Anti-Human MET Recombinant Antibody (TAB-521CL) (CAT#: TAB-521CL)
Recombinant Humanized monoclonal antibody expressed in CHO binding to Human MET. This antibody is an anti-c-Met antibody with significant preclinical single-agent activity against MA human xenograft tumors. This antibody was well tolerated and appeared to have substantial single-agent activity. In this small cohort of gastric patients MA appears to be more common in treatment-refractory tumors than in primary untreated tumors, suggesting that screening efforts should focus on this treatment-refractory patient population.
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ELISA
Figure 1 Anti-Human MET Recombinant Antibody (TAB-521CL) in ELISA
ELISA analysis of TAB-521CL was performed by coating with Recombinant Human MET Protein.
WB
Figure 2 Anti-Human MET Recombinant Antibody (TAB-521CL) in WB
Western blot analysis of TAB-521CL was performed with Recombinant Human MET Protein
Lane 1: Non-Reducing Antigen (0.5μg)
Lane 2: Reducing Antigen (0.5μg)
Specifications
- Derivation
- Humanized
- Type
- Antibody
- Species Reactivity
- Human
- Applications
- WB, FuncS
- Related Disease
- Cancer; Solid Tumors
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions
- Storage
- Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Functional Assay and Western Blot. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- MET; MET proto-oncogene, receptor tyrosine kinase; HGFR; AUTS9; RCCP2; c-Met; hepatocyte growth factor receptor; SF receptor; HGF receptor; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyr
- Gene ID
- 4233
- UniProt ID
- A0A024R759
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G049E | Anti-MET immunotoxin (Fab)-PE | Cytotoxicity assay, Function study |
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To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-521CL, RRID: AB_3111967)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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