Recombinant Human Anti-Human MPL Agonist Antibody (12D5)
CAT#: MOB-109LC
This product is a fully human anti-human MPL antibody with agonistic activity. The clone 12D5 is a recombinant antibody that binds to human MPL with a relatively high affinity of about 10 nM, it is shown to influence the replication, differentiation or maturation of blood cells and can be used in the study of thrombocytopenia.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to nuclear membrane & plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7619/1825_E1_28_cr5abb7d728bca3_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enriched (HEL)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117400-MPL
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Specifications
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Human MPL
- Species Reactivity
- Human
- Clone
- 12D5
- Applications
- Flow cytometry, Functional study, Enzyme-linked immunosorbent assay
- Related Disease
- Thrombocytopenia
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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|---|---|---|---|
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| HPAB-0567-CN | Mouse Anti-MPL Recombinant Antibody (HPAB-0567-CN) | ELISA, FC, Block | Mouse IgG2b, κ |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-155CQ | Human Anti-MPL Recombinant Antibody (TAB-155CQ) | ELISA, FC, FuncS | Human IgG1 |
| TAB-155CQ-S(P) | Human Anti-MPL Recombinant Antibody; scFv Fragment (TAB-155CQ-S(P)) | ELISA, FC, WB | Human scFv |
| TAB-155CQ-F(E) | Human Anti-MPL Recombinant Antibody; Fab Fragment (TAB-155CQ-F(E)) | ELISA, FC, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-156CQ | Anti-Human MPL Recombinant Antibody (TA136) | ELISA, FC | |
| TAB-157CQ | Anti-Human MPL Recombinant Antibody (VB22B) | ELISA, FC | |
| TAB-156CQ-S(P) | Anti-Human MPL Recombinant Antibody scFv Fragment (TA136) | ELISA, FC | |
| TAB-157CQ-S(P) | Anti-Human MPL Recombinant Antibody scFv Fragment (VB22B) | ELISA, FC | |
| TAB-156CQ-F(E) | Anti-Human MPL Recombinant Antibody Fab Fragment (TA136) | ELISA, FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2272 | Hi-Affi™ Recombinant Rabbit Anti-MPL Monoclonal Antibody (DS2272AB) | FC, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-108LC | Recombinant Human Anti-Human MPL Agonist Antibody (12B5) | FC, FunS, ELISA | Human antibody |
| MOB-110LC | Recombinant Human Anti-Human MPL Agonist Antibody (12E10) | FC, FunS, ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0566-CN-S(P) | Mouse Anti-MPL Recombinant Antibody; scFv Fragment (HPAB-0566-CN-S(P)) | ELISA, FC, Block | Mouse scFv |
| HPAB-0567-CN-S(P) | Mouse Anti-MPL Recombinant Antibody; scFv Fragment (HPAB-0567-CN-S(P)) | ELISA, FC, Block | Mouse scFv |
| HPAB-0568-CN-S(P) | Mouse Anti-MPL Recombinant Antibody; scFv Fragment (HPAB-0568-CN-S(P)) | ELISA, FC, Block | Mouse scFv |
| HPAB-0411-YC-S(P) | Mouse Anti-MPL Recombinant Antibody; scFv Fragment (HPAB-0411-YC-S(P)) | FC, ELISA | Mouse scFv |
| HPAB-0412-YC-S(P) | Human Anti-MPL Recombinant Antibody scFv Fragment (HPAB-0412-YC-S(P)) | FC, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0566-CN-F(E) | Mouse Anti-MPL Recombinant Antibody; Fab Fragment (HPAB-0566-CN-F(E)) | ELISA, FC, Block | Mouse Fab |
| HPAB-0567-CN-F(E) | Mouse Anti-MPL Recombinant Antibody; Fab Fragment (HPAB-0567-CN-F(E)) | ELISA, FC, Block | Mouse Fab |
| HPAB-1580-FY-S(P) | Mouse Anti-MPL Recombinant Antibody; scFv Fragment (HPAB-1580-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-1581-FY-S(P) | Mouse Anti-MPL Recombinant Antibody; scFv Fragment (HPAB-1581-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-1582-FY-S(P) | Mouse Anti-MPL Recombinant Antibody; scFv Fragment (HPAB-1582-FY-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY143 | Human Anti-MPL (clone 5E5) scFv-Fc Chimera | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC552 | Recombinant Anti-MPL Vesicular Antibody, EV Displayed (VS-0425-YC552) | Block, ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC127 | Recombinant Anti-MPL (Bin I x Bin II) Biparatopic Antibody, Tandem scFv | Block, ELISA, FC | Tandem scFv |
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