Recombinant Mouse Antibody (6D8) is capable of binding to MSP2 , expressed in Chinese Hamster Ovary cells (CHO).
Figure 1 MSP2 may be polymeric on the merozoite surface.
Binding of monoclonal antibodies 6D8 to monomeric (triangles) MSP2 as shown by ELISA.
Adda, C. G., Murphy, V. J., Sunde, M., Waddington, L. J., Schloegel, J., Talbo, G. H., ... & Hodder, A. N. (2009). Plasmodium falciparum merozoite surface protein 2 is unstructured and forms amyloid-like fibrils. Molecular and biochemical parasitology, 166(2), 159-171.
Figure 2 MSP2 may be polymeric on the merozoite surface.
Western blotting experiments of recombinant 3D7 (lane 1) and FC27 MSP2 (lane 2), the PK-resistant core (lane 3), and 3D7 (lane 4) and D10 (lane 5) parasite lysates probed with mAbs 6D8 and 11E1 and polyclonal sheep sera raised against 3D7 and FC27 MSP2.
Adda, C. G., Murphy, V. J., Sunde, M., Waddington, L. J., Schloegel, J., Talbo, G. H., ... & Hodder, A. N. (2009). Plasmodium falciparum merozoite surface protein 2 is unstructured and forms amyloid-like fibrils. Molecular and biochemical parasitology, 166(2), 159-171.
Figure 3 MSP2 may be polymeric on the merozoite surface.
Immunofluorescence microscopy data showing mAb11E1 binding to the 3D7 parasite strain only (f, fluorescence; n, nuclear stain; b, bright field).
Adda, C. G., Murphy, V. J., Sunde, M., Waddington, L. J., Schloegel, J., Talbo, G. H., ... & Hodder, A. N. (2009). Plasmodium falciparum merozoite surface protein 2 is unstructured and forms amyloid-like fibrils. Molecular and biochemical parasitology, 166(2), 159-171.
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CAT | Product Name | Application | Type |
---|---|---|---|
PABL-644 | Recombinant Human Anti-Merozoite surface protein 2 (MSP2) Antibody (h6D8) | WB | IgG |
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