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    Anti-Human MSTN Recombinant Antibody (H2L2) (CAT#: TAB-459MZ)

    This antibody which binds to myostatin can be potentially used in the treatment or prophylaxis of diseases associated with any one or a combination of decreased muscle mass, muscle strength and muscle function.

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    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    We require custom production
    • Published Data
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    FuncS

    Figrue 1 shows binding of the H2L2-N54Q-C91S humanised anti-myostatin antibody variant to myostatin following treatment of the antibody with or without ammonium bicarbonate which can induce deamidation of the antibody.

    Figrue 1 shows binding of the H2L2-N54Q-C91S humanised anti-myostatin antibody variant to myostatin following treatment of the antibody with or without ammonium bicarbonate which can induce deamidation of the antibody.

    FuncS

    Figure 2 shows binding of the H2L2-C91S humanised anti-myostatin antibody variant to myostatin following treatment of the antibody with or without ammonium bicarbonate which can induce deamidation of the antibody.

    Figure 2 shows binding of the H2L2-C91S humanised anti-myostatin antibody variant to myostatin following treatment of the antibody with or without ammonium bicarbonate which can induce deamidation of the antibody.

    Inhib

    Figure 3 shows the H2L2-N54Q, H2L2-C91S, H2L2-N54Q-C91S humanised anti-myostatin antibody variants, H0L0, H2L2 and 10B3C inhibition of myostatin- induced activation of cell signalling, resulting in luciferase expression in A204 cells.

    Figure 3 shows the H2L2-N54Q, H2L2-C91S, H2L2-N54Q-C91S humanised anti-myostatin antibody variants, H0L0, H2L2 and 10B3C inhibition of myostatin- induced activation of cell signalling, resulting in luciferase expression in A204 cells.

    ELISA

    Figure 4 shows the binding of purified H2L2-N54Q, H2L2-C91S, H2L2- N54Q-C91S humanised anti-myostatin antibody variants, H2L2, HOLO and 10B3C (HCLC) to myostatin by ELISA.

    Figure 4 shows the binding of purified H2L2-N54Q, H2L2-C91S, H2L2- N54Q-C91S humanised anti-myostatin antibody variants, H2L2, HOLO and 10B3C (HCLC) to myostatin by ELISA.

    Inhib

    Figure 5 shows 10B3, 10B3C, HOLO and H2L2 inhibition of myostatin- induced activation of cell signalling, resulting in luciferase expression in A204 cells.

    Figure 5 shows 10B3, 10B3C, HOLO and H2L2 inhibition of myostatin- induced activation of cell signalling, resulting in luciferase expression in A204 cells.


    Specifications

    • Host Species
    • Human
    • Type
    • Humanized antibody
    • Specificity
    • Human
    • Clone
    • H2L2
    • Applications
    • ELISA, FuncS, Inhib
    • Related Disease
    • Muscle atrophy

    Applications

    • Application Notes
    • This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Functional Assay, Inhibition.

    Target

    • Alternative Names
    • MSTN; myostatin; GDF8; MSLHP; growth/differentiation factor 8; GDF-8; growth differentiation factor 8

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    See other products for "Clone H2L2"

    See other products for "MSTN"

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    Please select product type
    Mouse Antibody Products Humanized Antibody Products Chimeric Antibody Products Human Antibody Products IgG Antibody Products ScFv Antibody Products Fab Antibody Products Antibody Magnetic Beads ScFv-Fc Chimera Products
    CAT Product Name Application Type
    TAB-0476CL Mouse Anti-MSTN Recombinant Antibody (TAB-0476CL) ELISA, WB Mouse IgG
    TAB-0477CL Mouse Anti-MSTN Recombinant Antibody (TAB-0477CL) ELISA, WB Mouse IgG
    TAB-0478CL Mouse Anti-MSTN Recombinant Antibody (TAB-0478CL) ELISA, WB Mouse IgG
    TAB-0479CL Mouse Anti-MSTN Recombinant Antibody (TAB-0479CL) ELISA, WB Mouse IgG
    TAB-0480CL Mouse Anti-MSTN Recombinant Antibody (TAB-0480CL) ELISA, WB Mouse IgG

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