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    Humanized Anti-MUC1 Recombinant Antibody (clone Cantuzumab) (CAT#: TAB-166)

    This product is a humanized (from mouse) IgG1, κ antibody that can recognize human MUC1.

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    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
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    Fc Engineering :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line RPTEC TERT1
    Figure 1 IF staining of human cell line RPTEC TERT1
    (Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8855/1789_B9_13_cr596f381e20667_selected.jpg
    Figure 2 IHC staining of human stomach
    Figure 2 IHC staining of human stomach
    (Immunohistochemical staining of human stomach shows strong membranous positivity in glandular cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1986/ihc_selected.jpg
    Figure 3 IF staining of human cell line A-431
    Figure 3 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8855/100_E7_1_blue_red_green.jpg
    Figure 4 IF staining of human cell line U-2 OS
    Figure 4 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8855/101_E7_1_blue_red_green.jpg
    Normal Tissue
    Figure 5 Stomach
    Figure 5 Stomach
    (Glandular cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36/155175_A_2_1.jpg
    Figure 6 Colon
    Figure 6 Colon
    (Endocrine cells
    Staining:High
    Intensity: Strong
    Enterocytes
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Goblet cells
    Staining:High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36/155175_A_9_3.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Collecting ducts
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Distal tubules
    Staining:High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36/155175_A_8_5.jpg
    Figure 8 Testis
    Figure 8 Testis
    (Elongated or late spermatids
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36/155175_A_6_6.jpg
    RNA Expression
    Figure 9 RNA cell line category: Group enriched (CAPAN-2, OE19, RPTEC TERT1, T-47d)
    Figure 9 RNA cell line category: Group enriched (CAPAN-2, OE19, RPTEC TERT1, T-47d)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185499-MUC1

    Specifications

    • Immunogen
    • Synthetic peptides conjugated with KLH and mixed with complete Freund`s adjuvant
    • Host Species
    • Human
    • Derivation
    • Humanized (from mouse)
    • Type
    • Humanized (from mouse) IgG1, κ
    • Specificity
    • Human MUC1
    • Species Reactivity
    • Human
    • Clone
    • Cantuzumab
    • Applications
    • IP, IF, FuncS, FC, Neut, ELISA, ICC

    Product Property

    • Purification
    • Protein A/G Purified
    • Purity
    • >95% as determined by SDS-PAGE and HPLC analysis
    • Concentration
    • Please refer to the vial label for the specific concentration
    • Buffer
    • PBS
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • This antibody has been reported for use in Immunoprecipitation, Immunofluorescence, Functional Assay, Flow Cytometry, Neutralization, Enzyme-linked Immunosorbent Assay, Immunocytochemistry.

    Target

    • Alternative Names
    • EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC; mucin-1; H23 antigen; breast carcinoma-associated antigen DF3; cancer antigen 15-3; carcinoma-associated mucin; episialin; krebs von den Lungen-6; mucin 1, transmembrane; peanut-reactive urinary mucin; polymorphic epithelial mucin; tumor associated epithelial mucin; tumor-associated epithelial membrane antigen

    Related Resources

    • Biosimilar Overview
    Please refer to Cantuzumab Mertansine Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Cantuzumab Mertansine.

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    NAB-2049-VHH Recombinant Anti-human MUC1 VHH Single Domain Antibody WB, IP, ChiP, Neut, ELISA Llama VHH
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    HPAB-AP505-YC Recombinant Camel Anti-MUC1 Single Domain Antibody (HPAB-AP505-YC) ELISA Camel VHH
    HPAB-0736-YJ-VHH Camelid Anti-MUC1 Recombinant Single Domain Antibody (HPAB-0736-YJ-VHH) ELISA Camelid VHH
    HPAB-0737-YJ-VHH Camelid Anti-MUC1 Recombinant Single Domain Antibody (HPAB-0737-YJ-VHH) ELISA Camelid VHH

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