Rabbit Anti-ADIPOQ Recombinant Antibody (clone HA3) (CAT#: PABL-472)

Recombinant Rabbit Antibody (HA3) is capable of binding to Mouse adipocyte.


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WB

Figure 1 Plasma aP2 levels in HFD-fed mice treated with vehicle, CA33, or HA3 for 3 weeks (n = 10 mice per group).

Figure 1 Plasma aP2 levels in HFD-fed mice treated with vehicle, CA33, or HA3 for 3 weeks (n = 10 mice per group).

Western blots were carried out to detect aP2 in the serum of three mice from each group.

Burak, M. F., Inouye, K. E., White, A., Lee, A., Tuncman, G., Calay, E. S., ... & Lightwood, D. (2015). Development of a therapeutic monoclonal antibody that targets secreted fatty acid–binding protein aP2 to treat type 2 diabetes. Science translational medicine, 7(319), 319ra205-319ra205.

FuncS

Figure 2 Blood glucose levels in obese mice on HFD before and after a 4-week treatment of vehicle or anti-aP2 mAbs.

Figure 2 Blood glucose levels in obese mice on HFD before and after a 4-week treatment of vehicle or anti-aP2 mAbs.

Blood glucose levels were measured after 6 hours of daytime food withdrawal.

Burak, M. F., Inouye, K. E., White, A., Lee, A., Tuncman, G., Calay, E. S., ... & Lightwood, D. (2015). Development of a therapeutic monoclonal antibody that targets secreted fatty acid–binding protein aP2 to treat type 2 diabetes. Science translational medicine, 7(319), 319ra205-319ra205.


Specifications

  • Immunogen
  • Mouse adiponectin, C1Q and collagen domain containing
  • Host Species
  • Rabbit
  • Derivation
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Mouse adipocyte
  • Species Reactivity
  • Mouse
  • Clone
  • HA3
  • Applications
  • WB, FuncS

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Western Blot and Function Assay.

Target

  • Alternative Names
  • ADIPOQ; adiponectin, C1Q and collagen domain containing; APN; Acdc; apM1; 30kDa; GBP28; adipo; Acrp30; adiponectin; 30 kDa adipocyte complement-related protein; adipocyte complement related protein; adipocyte complement-related 30 kDa protein; adipocyte, C1Q and collagen domain containing; adipocyte, C1q and collagen domain-containing protein; adipocyte-specific protein AdipoQ

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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