Anti-NGF antibody is a Rat antibody of IgG class that binds to an NGF. The rat monoclonal antibody (mAb) has been shown to bind to NGF with nanomolar affinity and with high specificity and to effectively neutralize its in vitro and in vivo biological functions.
Figure 1 IP and WB of transgenic and wild-type mice.
IP and WB of cortex extracts from male(M) and female(F) TgProNGF#72 and wild-type (WT) mice. IP on extracts from cortex(CTX) with anti-NGF aD11 antibody, followed by WB with anti-NGF or anti-proNGF antibody, as described in Tiveron et al.(2013). Are presentative WB probed with anti-proNGF(PAb Alomone),(top)or anti-NGFM20 (Santa Cruz)(bottom) is shown. TgproNGF#72 and wild type mice,male and female,were analyzed.
Malerba, F., Paoletti, F., & Cattaneo, A. (2016). NGF and proNGF reciprocal interference in immunoassays: open questions, criticalities, and ways forward. Frontiers in molecular neuroscience, 9, 63.
Figure 2 EmaxNGF Promega:NGFS tandard curves.
NGF standard curves carried out by usingr at mAb Promega(triangles) and mAb aD11(Cattaneoetal.,1988) (squares) as primary antibody.
Malerba, F., Paoletti, F., & Cattaneo, A. (2016). NGF and proNGF reciprocal interference in immunoassays: open questions, criticalities, and ways forward. Frontiers in molecular neuroscience, 9, 63.
Figure 3 SPR analysis-calibration curve sobtained with proNGF and NG Fover the panel of different antibodies.
Different pro NGF concentrations tested on anti-NGFmAb aD11. ConcentrationsinnM(fromtop): 500,333,222,148,98, 65,33,16,8,4,2,1,0.5.
Malerba, F., Paoletti, F., & Cattaneo, A. (2016). NGF and proNGF reciprocal interference in immunoassays: open questions, criticalities, and ways forward. Frontiers in molecular neuroscience, 9, 63.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-111 | Anti-Human NGF Recombinant Antibody (Tanezumab) | ELISA, FuncS, Inhib | IgG2 |
TAB-686CL | Anti-Human NGF Therapeutical Antibody (PG110) | FuncS | Antibody |
TAB-501MZ | Anti-Human NGF Recombinant Antibody (αD11. H67) | ELISA | Humanized antibody |
TAB-501MZ-S(P) | Anti-Human NGF Recombinant Antibody scFv Fragment (αD11. H67) | ELISA, IRMA, RIA, IHC | Humanized antibody |
TAB-501MZ-F(E) | Anti-Human NGF Recombinant Antibody Fab Fragment (αD11. H67) | ELISA, IRMA, RIA, IHC | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-659 | Human Anti-NGF Recombinant Antibody (clone APE1531); scFv Fragment | WB, FuncS | Human scFv |
PFBC-235 | Recombinant Human Anti-NGF Antibody Fab Fragment (APE1531) | ELISA, WB | Fab |
HPAB-0688-CN-S(P) | Human Anti-NGF Recombinant Antibody; scFv Fragment (HPAB-0688-CN-S(P)) | WB, ELISA | Human scFv |
HPAB-0275CQ-S(P) | Human Anti-NGF Recombinant Antibody; scFv Fragment (HPAB-0275CQ-S(P)) | ELISA, Neut | Human scFv |
HPAB-1789-FY-F(E) | Human Anti-NGF Recombinant Antibody; Fab Fragment (HPAB-1789-FY-F(E)) | ELISA | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0331CL | Mouse Anti-NGF Recombinant Antibody (TAB-0331CL) | Neut, ELISA, Inhib, FuncS | Mouse IgG |
TAB-500MZ-S(P) | Anti-Human NGF Recombinant Antibody scFv Fragment (MNAC13) | ELISA, IRMA, RIA, IHC | |
TAB-502MZ-S(P) | Anti-Dog NGF Recombinant Antibody scFv Fragment (NV-01) | SDS-PAGE | |
TAB-503MZ-S(P) | Mouse Anti-NGF Recombinant Antibody; scFv Fragment (TAB-503MZ-S(P)) | ELISA | Mouse scFv |
PABX-146-F (E) | Recombinant Rat Anti-NGF Antibody Fab Fragment (αD11) | Neut, FC, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-509MZ | Human Anti-NGF Recombinant Antibody (TAB-509MZ) | ELISA | Chimeric (mouse/human) IgG |
TAB-510MZ | Human Anti-NGF Recombinant Antibody (TAB-510MZ) | ELISA, FuncS | Chimeric (mouse/human) IgG |
TAB-509MZ-S(P) | Mouse Anti-NGF Recombinant Antibody; scFv Fragment (TAB-509MZ-S(P)) | ELISA | Mouse scFv |
TAB-509MZ-F(E) | Human Anti-NGF Recombinant Antibody; Fab Fragment (TAB-509MZ-F(E)) | ELISA | Chimeric (mouse/human) Fab |
TAB-510MZ-F(E) | Human Anti-NGF Recombinant Antibody; Fab Fragment (TAB-510MZ-F(E)) | ELISA | Chimeric (mouse/human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-512MZ | Human Anti-NGF Recombinant Antibody (TAB-512MZ) | ELISA, RIA, FC, SPR, Inhib | Human IgG |
TAB-513MZ | Human Anti-NGF Recombinant Antibody (TAB-513MZ) | ELISA, RIA, FC, SPR, Inhib | Human IgG |
TAB-512MZ-S(P) | Human Anti-NGF Recombinant Antibody; scFv Fragment (TAB-512MZ-S(P)) | ELISA, RIA, FC | Human scFv |
TAB-512MZ-F(E) | Human Anti-NGF Recombinant Antibody; Fab Fragment (TAB-512MZ-F(E)) | ELISA, RIA, FC | Human Fab |
TAB-513MZ-F(E) | Human Anti-NGF Recombinant Antibody; Fab Fragment (TAB-513MZ-F(E)) | ELISA, RIA, FC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0852MZ | Chicken Anti-NGF Polyclonal IgY | ELISA | Chicken antibody |
BRD-1134MZ | Chicken Anti-Beta NGF Polyclonal IgY | ELISA, WB, IHC | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-146-S (P) | Rat Anti-NGF Recombinant Antibody (clone αD11) | Neut, FC, FuncS | Rat scFv |
MOR-2439 | Hi-Affi™ Recombinant Rabbit Anti-NGF Monoclonal Antibody (DS2439AB) | WB, ICC, IHC-P, IHC-P | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1764CQ | Recombinant Mouse Anti-NGF Antibody (CBL293) | Neut | IgG1 |
NEUT-1765CQ | Recombinant Mouse Anti-NGF Antibody (12A29) | ELISA, Neut | IgG1 |
NEUT-1766CQ | Recombinant Mouse Anti-NGF Antibody (M85-2B) | ELISA, Neut, WB | IgG2b, κ |
NEUT-1767CQ | Recombinant Mouse Anti-Ngf Antibody (27/21) | ELISA, Neut | IgG1 |
NEUT-1769CQ | Recombinant Mouse Anti-NGF Antibody (AS18) | Neut | IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1768CQ | Recombinant Mouse Anti-NGF Antibody (aD11) | IF, BL, ELISA, IHC | IgG1, κ |
NEUT-1772CQ | Recombinant Mouse Anti-NGF Antibody (25623.1) | Dot, ELISA, Inhib | IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0028YC | Rat Anti-NGF Recombinant Antibody (clone G 30) | WB, ICC, FuncS | Rat IgG2a |
HPAB-0688-CN | Human Anti-NGF Recombinant Antibody (HPAB-0688-CN) | WB, ELISA | Human IgG4 |
FAMAB-1225CQ | Mouse Anti-NGF Recombinant Antibody (clone alphaD11) | Block, ELISA, IF, IHC | Mouse IgG1 |
HPAB-A1277-YJ | Human Anti-NGF Recombinant Antibody (clone APE424) | WB, ELISA, FC | Humanized IgG |
HPAB-A1278-YJ | Human Anti-NGF Recombinant Antibody (clone APE520) | WB, ELISA, FC | Humanized IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-025ML | Afuco™ Anti-NGF ADCC Recombinant Antibody (Frunevetmab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
AFC-TAB-031ML | Afuco™ Anti-NGF ADCC Recombinant Antibody (Ranevetmab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
AFC-TAB-111 | Afuco™ Anti-NGF ADCC Recombinant Antibody (Tanezumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-110 | Afuco™ Anti-NGF Recombinant Antibody (AFC-TAB-110), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | Human IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0385-WJ-F(E) | Mouse Anti-NGF Recombinant Antibody; Fab Fragment (HPAB-0385-WJ-F(E)) | ELISA, FC | Mouse Fab |
HPAB-AP153-YC-F(E) | Canine Anti-NGF Recombinant Antibody; Fab Fragment (HPAB-AP153-YC-F(E)) | ELISA, FuncS | Canine Fab |
HPAB-AP154-YC-F(E) | Canine Anti-NGF Recombinant Antibody; Fab Fragment (HPAB-AP154-YC-F(E)) | ELISA, FuncS | Canine Fab |
HPAB-AP155-YC-F(E) | Canine Anti-NGF Recombinant Antibody; Fab Fragment (HPAB-AP155-YC-F(E)) | ELISA, FuncS | Canine Fab |
HPAB-N0190-YC-F(E) | Human Anti-NGF Recombinant Antibody (clone NOV009YC); Fab Fragment | ELISA | Human Fab |
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