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    Anti-Human NOTUM Recombinant Antibody (SC2.A106) (CAT#: TAB-565MZ)

    This human Notum neutralizing monoclonal antibody is able to block the Notum activity and impairs Notum mediated proliferation. It dose not inhibit the activity of murine or macaque Notum despite showing cross reactivity with murine Notum.

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    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Published Data
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    FuncS

    Figure 1 are graphical representations of a canonical Wnt3A assay as used to measure the effects of Notum modulators SC2.D2.2 and SC2.A106 (aka 10B3) on soluble Notum constructs Notum-His and Notum-hFc at various concentrations as normalized against uninhibited Wnt-induced luciferase activity.

    Figure 1 are graphical representations of a canonical Wnt3A assay as used to measure the effects of Notum modulators SC2.D2.2 and SC2.A106 (aka 10B3) on soluble Notum constructs Notum-His and Notum-hFc at various concentrations as normalized against uninhibited Wnt-induced luciferase activity.


    Specifications

    • Host Species
    • Mouse
    • Specificity
    • Human
    • Species Reactivity
    • Mouse
    • Clone
    • SC2.A106 (aka 10B3)
    • Applications
    • FuncS
    • Related Disease
    • Hyperproliferative disorders

    Applications

    • Application Notes
    • This antibody has been reported for use in Functional Assay.

    Target

    • Alternative Names
    • NOTUM; notum pectinacetylesterase homolog (Drosophila); protein notum homolog

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Clone SC2.A106 (aka 10B3)"

    See other products for "NOTUM"

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    Please select product type
    Mouse Antibody Products Humanized Antibody Products
    CAT Product Name Application Type
    TAB-564MZ Anti-Human NOTUM Recombinant Antibody (SC2.D2.2) FuncS, Inhib
    TAB-567MZ Mouse Anti-NOTUM Recombinant Antibody (TAB-567MZ) ELISA Mouse IgG2a
    TAB-568MZ Mouse Anti-NOTUM Recombinant Antibody (TAB-568MZ) ELISA Mouse IgG2b
    TAB-564MZ-S(P) Anti-Human NOTUM Recombinant Antibody scFv Fragment (SC2.D2.2) ELISA
    TAB-565MZ-S(P) Anti-Human NOTUM Recombinant Antibody scFv Fragment (SC2.A106) ELISA

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