Anti-Human NOTUM Recombinant Antibody (SC2.A106) (CAT#: TAB-565MZ)
This human Notum neutralizing monoclonal antibody is able to block the Notum activity and impairs Notum mediated proliferation. It dose not inhibit the activity of murine or macaque Notum despite showing cross reactivity with murine Notum.
Specific Inquiry
FuncS
Figure 1 are graphical representations of a canonical Wnt3A assay as used to measure the effects of Notum modulators SC2.D2.2 and SC2.A106 (aka 10B3) on soluble Notum constructs Notum-His and Notum-hFc at various concentrations as normalized against uninhibited Wnt-induced luciferase activity.
Specifications
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Mouse
- Clone
- SC2.A106 (aka 10B3)
- Applications
- FuncS
- Related Disease
- Hyperproliferative disorders
Applications
- Application Notes
- This antibody has been reported for use in Functional Assay.
Target
- Alternative Names
- NOTUM; notum pectinacetylesterase homolog (Drosophila); protein notum homolog
- Gene ID
- 147111
- UniProt ID
- Q6P988
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Mouse Antibody Products
Humanized Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-564MZ | Anti-Human NOTUM Recombinant Antibody (SC2.D2.2) | FuncS, Inhib | |
| TAB-564MZ-S(P) | Anti-Human NOTUM Recombinant Antibody scFv Fragment (SC2.D2.2) | ELISA | |
| TAB-565MZ-S(P) | Anti-Human NOTUM Recombinant Antibody scFv Fragment (SC2.A106) | ELISA | |
| TAB-567MZ-S(P) | Mouse Anti-NOTUM Recombinant Antibody; scFv Fragment (TAB-567MZ-S(P)) | ELISA | Mouse scFv |
| TAB-568MZ-S(P) | Mouse Anti-NOTUM Recombinant Antibody; scFv Fragment (TAB-568MZ-S(P)) | ELISA | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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