Afuco™ Anti-Human NTRK1 ADCC Recombinant Antibody (MNAC13), ADCC Enhanced
CAT#: AFC-668CL
Anti-NTRK1 ADCC Enhanced Antibody (MNAC13) is an ADCC enhanced antibody produced by our Afuco™ platform. MNAC13 is a mouse monoclonal antibody which recognizes the neurotrophin receptor TrkA with high affinity and specificity. It displays a neutralizing activity toward the NGF/TrkA interaction. A full biochemical and structural characterization of the MNAC13 antibody may be appropriate for therapeutic approaches in neuropathy and inflammatory pain states.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SH-SY5Y
Immunofluorescent staining of human cell line SH-SY5Y shows localization to cytosol & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76570/1680_E8_5_selected.jpg
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Specifications
- Host Species
- Humanized
- Derivation
- Mouse
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Neuropathy Pain; Inflammatory Pain
Product Property
- Purity
- >90% assessed by SDS-PAGE
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Target
- Alternative Names
- NTRK1; neurotrophic tyrosine kinase, receptor, type 1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA; high affinity nerve growth factor receptor; gp140trk; Oncogene TRK; tyrosine kinase receptor A; tropomyosin-related kinase A; TRK1-transforming tyrosine kinase protein
- Gene ID
- 4914
- UniProt ID
- P04629
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Related Diseases
EGFR Tyrosine Kinase Inhibitor Resistance
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
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| HPAB-0397-CN-F(E) | Human Anti-NTRK1 Recombinant Antibody Fab Fragment (HPAB-0397-CN-F(E)) | ELISA, Block | Human Fab |
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| HPAB-0729-CN-F(E) | Human Anti-NTRK1 Recombinant Antibody (clone CRB0088); Fab Fragment | WB, ELISA, FC | Human Fab |
| HPAB-0730-CN-F(E) | Human Anti-NTRK1 Recombinant Antibody (clone CRB0089_IgG4); Fab Fragment | WB, ELISA, FC | Human Fab |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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