Human Anti-Human NTRK1 Recombinant Antibody (CRB0089) (CAT#: TAB-170CQ)
This antibody recognises and binds to an epitope comprised in the TrkA amino acid sequence and inhibits NGF-mediated proliferative response in a dose dependent manner with an IC50 of approximately 43 nM. It is potentially useful in the treatment of diseases, including osteoarthritis pain and chronic pain.
Specific Inquiry
ELISA
Figure 1 Specificity ELISA of anti-TrkA CRB0089 IgG4 mAb versus human TrkA immunoadhesin (hTrkA-Fc) and human TrkB immunoadhesins (hTrkB-Fc), Human antigens were coated at 2 μg/mL.
FC
Figure 2 FACS analysis performed with Bioanalyzer 2100. A cell fluid chip-based fluorescent cytometric assay that runs on Bioanalyzer 2100 (Agilent) for fast characterization of Small population cell phenotypes was assessed.
Specifications
- Host Species
- Human
- Derivation
- Human SPLINT library
- Type
- Human antibody
- Specificity
- Human
- Species Reactivity
- Human, Mouse
- Clone
- CRB0089
- Applications
- ELISA, FC, WB
- Related Disease
- Osteoarthritis pain, chronic pain
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Flow Cytometry, Western Blot. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- NTRK1; Neurotrophic receptor tyrosine kinase 1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA; high affinity nerve growth factor receptor; gp140trk; Oncogene TRK; tyrosine kinase receptor A; tropomyosin-related kinase A; TRK1-transforming tyrosine kinase protein
- Gene ID
- 4914
- UniProt ID
- P04629
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone CRB0089"
See other products for "NTRK1"
Select a product category from the dropdown menu below to view related products.
Please select product type
Human Antibody Products
Chicken IgY Antibody Products
Mouse Antibody Products
Rabbit Monoclonal Antibody Products
ScFv Antibody Products
IgG Antibody Products
Fab Antibody Products
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-170CQ-S(P) | Human Anti-Human NTRK1 Recombinant Antibody scFv Fragment (CRB0089) | ELISA, FC, WB | Human antibody |
| TAB-170CQ-F(E) | Human Anti-Human NTRK1 Recombinant Antibody Fab Fragment (CRB0089) | ELISA, FC, WB | Human antibody |
| TAB-511MZ | Anti-Human NTRK1 Recombinant Antibody (CRB0089) | ELISA, WB, FC | Human antibody |
| TAB-511MZ-S(P) | Anti-Human NTRK1 Recombinant Antibody scFv Fragment (CRB0089) | ELISA, WB, FC | Human antibody |
| TAB-511MZ-F(E) | Anti-Human NTRK1 Recombinant Antibody Fab Fragment (CRB0089) | ELISA, WB, FC | Human antibody |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for TAB-170CQ. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
Application: ELISA, SPR, Inhib, FuncS
Application: ELISA, FC, WB, Block
Application: Block, IP, IF, FC
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, PD, Activ, PK, Stim
Application: FC, IHC, Cyt, FuncS
Application: ELISA, Neut, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
