Anti-Human NTRK3 Recombinant Antibody (2248) (CAT#: TAB-184CQ)

This antibody has the high affinity to TrkC and seems to recognize a determinant in domain 4. It appears that the epitope may be a linear epitope overlapping the boundary of domain 4 and 5.


Specific Inquiry
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  • Gene Expression
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Agonist

Figure 1 show agonist activity of murine monoclonal antibodies against trkC receptor demonstrated using KIRA (A and B) and PC 12 neurite outgrowth assay.

Figure 1 show agonist activity of murine monoclonal antibodies against trkC receptor demonstrated using KIRA (A and B) and PC 12 neurite outgrowth assay.

ELISA

Figure 2 demonstrates that agonist anti-trkC monoclonal antibodies recognize human trkC more efficiently than rat trkC.

Figure 2 demonstrates that agonist anti-trkC monoclonal antibodies recognize human trkC more efficiently than rat trkC.

ELISA

Figure 3 shows a representative example of epitope mapping using competition ELISA.

Figure 3 shows a representative example of epitope mapping using competition ELISA.

A biotinylated human anti-trkC 6.1.2 monoclonal antibody was incubated with immobilized trkC in the absence or presence of excess of various unlabeled anti-trkC monoclonal antibodies.


Specifications

  • Host Species
  • Mouse
  • Specificity
  • Human
  • Species Reactivity
  • Human
  • Clone
  • 2248
  • Applications
  • Agonist, ELISA
  • Related Disease
  • Amyotrophic lateral sclerosis (ALS)

Applications

  • Application Notes
  • This antibody has been reported for use in Agonist, Enzyme-linked Immunosorbent Assay.

Target

  • Alternative Names
  • NTRK3; Neurotrophic receptor tyrosine kinase 3; TRKC; gp145(trkC); NT-3 growth factor receptor; GP145-TrkC; ETV6-NTRK3 fusion; tyrosine kinase receptor C; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Rabbit Monoclonal Antibody

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0198-CN-S(P) Human Anti-NTRK3 Recombinant Antibody (clone A5); scFv Fragment ELISA, ICC Human scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0198-CN-F(E) Human Anti-NTRK3 Recombinant Antibody (clone A5); Fab Fragment ELISA, ICC Human Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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