This antibody has the high affinity to TrkC and seems to recognize a determinant in domain 4. It appears that the epitope may be a linear epitope overlapping the boundary of domain 4 and 5.
Figure 1 show agonist activity of murine monoclonal antibodies against trkC receptor demonstrated using KIRA (A and B) and PC 12 neurite outgrowth assay.
Figure 2 demonstrates that agonist anti-trkC monoclonal antibodies recognize human trkC more efficiently than rat trkC.
Figure 3 shows a representative example of epitope mapping using competition ELISA.
A biotinylated human anti-trkC 6.1.2 monoclonal antibody was incubated with immobilized trkC in the absence or presence of excess of various unlabeled anti-trkC monoclonal antibodies.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-2174z | Mouse Anti-NTRK3 Recombinant Antibody (clone 36A5) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG1 |
MOB-1790MZ | Recombinant Mouse Anti-Human NTRK3 Antibody (clone 5H6) | ELISA, ICC/IF, WB | Mouse antibody |
HPAB-0198-CN | Human Anti-NTRK3 Recombinant Antibody (clone A5) | ELISA, ICC | Human IgG2a, κ |
VS3-QX841 | Mouse Anti-NTRK3 Recombinant Antibody (clone 1454CT394.87.35) | WB | Mouse IgG1, κ |
VS3-WK1038 | Mouse Anti-NTRK3 Recombinant Antibody (VS3-WK1038) | WB | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-182CQ | Anti-Human NTRK3 Recombinant Antibody (6.4.1) | ELISA, WB | Human antibody |
TAB-182CQ-S(P) | Anti-Human NTRK3 Recombinant Antibody scFv Fragment (6.4.1) | ELISA, WB | Human antibody |
TAB-185CQ-S(P) | Anti-Human NTRK3 Recombinant Antibody scFv Fragment (6.1.2) | ELISA, WB | Human antibody |
TAB-182CQ-F(E) | Anti-Human NTRK3 Recombinant Antibody Fab Fragment (6.4.1) | ELISA, WB | Human antibody |
TAB-185CQ-F(E) | Anti-Human NTRK3 Recombinant Antibody Fab Fragment (6.1.2) | ELISA, WB | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-181CQ-S(P) | Mouse Anti-NTRK3 Recombinant Antibody; scFv Fragment (TAB-181CQ-S(P)) | ELISA, FC, IF, WB | Mouse scFv |
TAB-183CQ-S(P) | Anti-Human NTRK3 Recombinant Antibody scFv Fragment (2256) | ELISA, WB | |
TAB-184CQ-S(P) | Anti-Human NTRK3 Recombinant Antibody scFv Fragment (2248) | ELISA, WB | |
TAB-181CQ-F(E) | Mouse Anti-NTRK3 Recombinant Antibody; Fab Fragment (TAB-181CQ-F(E)) | ELISA, FC, IF, WB | Mouse Fab |
TAB-183CQ-F(E) | Anti-Human NTRK3 Recombinant Antibody Fab Fragment (2256) | ELISA, WB |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4350 | Hi-Affi™ Recombinant Rabbit Anti-NTRK3 Monoclonal Antibody (SI440DS) | ELISA | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0198-CN-S(P) | Human Anti-NTRK3 Recombinant Antibody (clone A5); scFv Fragment | ELISA, ICC | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0198-CN-F(E) | Human Anti-NTRK3 Recombinant Antibody (clone A5); Fab Fragment | ELISA, ICC | Human Fab |
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