1 0
Cart
    Inquiry
    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    Recombinant Anti-human NUP88 Intrabody [Tat] (CAT#: IAB-B063(T))

    Recombinant anti-NUP88 intrabody in fusion with HIV Tat works within cells to bind the nuclear pore protein NUP88, expressed in E. coli cells. Anti-Nup88 intrabody, an anti-sense oligonucleotide or nucleic acid which is complementary to at least a functional part of a Nup88 RNA or wherein the compound is a peptide, peptide-like or non-peptide Nup88 inhibitor which can be identified by contacting the compound or libraries of peptido- mimetics, peptides, DNA or cDNA expression, combinatorial chemistry or phage display with substantially purified Nup88, fragments thereof or structural analogues thereof.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/21816/if_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human stomach
    Figure 2 IHC staining of human stomach
    (Immunohistochemical staining of human stomach shows nuclear membrane positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2209/ihc_selected.jpg
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/21816/49954_B_8_5.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/21816/49954_A_9_3.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/21816/49954_A_9_4.jpg
    Figure 6 Gallbladder
    Figure 6 Gallbladder
    (Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/21816/49954_A_4_4.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/21816/49954_A_9_5.jpg
    Figure 8 Testis
    Figure 8 Testis
    (Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/21816/49954_A_6_6.jpg
    RNA Expression
    Figure 9 RNA cell line category: Low cell line specificity
    Figure 9 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000108559-NUP88

    Specifications

    • Immunogen
    • human nucleoporin 88kDa
    • Host Species
    • rabbit
    • Type
    • scFv-Tat
    • Cell Penetrating Peptide
    • TAT
      TAT was able to deliver different proteins, such as horseradish peroxidase and RNase A across cell membrane into the cytoplasm in different cell lines in vitro. The size range of proteins with effective delivery is from 30kDa to 120-150kDa. In one study, TAT-fused proteins are rapidly internalized by lipid raft−dependent macropinocytosis using a transducible TAT−Cre recombinase reporter assay on live cells. In another study, a TAT-fused protein was delivered into mitochondria of breast cancer cells and decreased the survival of breast cancer cells, which showed capability of TAT-fusion proteins to modulate mitochondrial function and cell survival. However, very few in vivo studies have succeeded. In one study, in vivo delivery of TAT- or penetratin-crosslinked Fab fragments yielded varied organ distributions and an overall increase in organ retention, which showed tissue localization.
    • Species Reactivity
    • human
    • Applications
    • Antibody assay: Enzyme-linked Immunosorbent Assay; Immunofluorescence; Neutralization; Functional studies

    Product Property

    • Purity
    • 95% by HPLC
    • Storage
    • Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.

    Target

    • Alternative Names
    • NUP88; nucleoporin 88kDa; nuclear pore complex protein Nup88; karyoporin; nucleoporin 88kD; nucleoporin Nup88; 88 kDa nucleoporin; nuclear pore complex protein 88

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "NUP88"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Intrabody Products
    CAT Product Name Application Type
    MOB-2733z Mouse Anti-NUP88 Recombinant Antibody (clone 39C9) WB, ELISA, IF, IP Mouse IgG2b, κ

    Customer Reviews and Q&As

    Submit a review or a question

    There are currently no Customer reviews or questions for IAB-B063(T). Click the button above to contact us or submit your feedback about this product.

    Popular products with customers

    Figure 5 Anti-Human TNFSF11 Antibody (TAB-H18) in DB

    Human Anti-TNFSF11 Recombinant Antibody (TAB-H18) (CAT# TAB-H18)
    Application: Neut, ELISA, IF, IP, FuncS, FC, ICC

    Figure 2 Anti-Human CSF1R Antibody (TAB-H23) in ELISA

    Anti-Human CSF1R Recombinant Antibody (TAB-H23) (CAT# TAB-H23)
    Application: WB, ELISA, IP, FC, FuncS, Neut, IF

    Figure 2 Anti-Human MUC5AC Recombinant Antibody (TAB-200) in SEC-HPLC

    Anti-Human MUC5AC Recombinant Antibody (TAB-200) (CAT# TAB-200)
    Application: IP, IF, FuncS, FC, Neut, ELISA, ICC

    Figure 3 Anti-CD40 Antibody (TAB-126CL) in Dot Blot

    Human Anti-CD40 Recombinant Antibody (TAB-126CL) (CAT# TAB-126CL)
    Application: Block, Cyt, FuncS, Inhib

    Figure 3 Anti-Human C5 Recombinant Antibody (TP-092CL) in ELISA

    Human Anti-Human C5 Rcombinant Antibody (TP-092CL) (CAT# TP-092CL)
    Application:

    Figure 1 Recombinant Human Anti-DENV E proteins Antibody (PABL-067) in SDS-PAGE

    Recombinant Human Anti-DENV E proteins Antibody (5J7) (CAT# PABL-067)
    Application: ELISA, Neut, FuncS

    Figure 5 Recombinant Human Anti-IAV HA Antibody (5J8) (PABL-207) in Dot Blot

    Recombinant Human Anti-IAV HA Antibody (5J8) (CAT# PABL-207)
    Application: FuncS

    Figure 5 Human Anti-HIV Env Recombinant Antibody (PABL-509) in ELISA

    Human Anti-HIV Env Recombinant Antibody (clone PGT121) (CAT# PABL-509)
    Application: ELISA, Neut

    Figure 3 Anti-Human PERP Antibody (TAB-1017CL) in Flow cytometry

    Anti-Human PERP Recombinant Antibody (KM3411) (CAT# TAB-1017CL)
    Application: FC

    Figure 2 Anti-Human RNF43 Recombinant Antibody (TAB-328CT) in HPLC

    Humanized Anti-RNF43 Recombinant Antibody (TAB-328CT) (CAT# TAB-328CT)
    Application: WB, ELISA, FC, IHC, IP

    Figure 1 Anti-Human VEGF Recombinant Antibody (TAB-298CQ) in ELISA

    Human Anti-VEGF Recombinant Antibody (TAB-298CQ) (CAT# TAB-298CQ)
    Application: ELISA, Inhib

    Figure 3 Rat Anti-IL18 Recombinant Antibody (HPAB-0067-YC-F(E)) in ELISA

    Rat Anti-IL18 Recombinant Antibody (clone 2C10); Fab Fragment (CAT# HPAB-0067-YC-F(E))
    Application: Neut

    Figure 5 Rabbit Anti-T7 RNA Polymerase Antibody, HRP (MOB-0296MC-HRP) in Dot Blot

    Rabbit Anti-T7 RNA Polymerase Antibody (CAT# MOB-0296MC)
    Application: ELISA, WB

    Figure 3 Anti-C5 Recombinant Antibody (PABC-462) in DB

    Human Anti-C5 Recombinant Antibody (PABC-462) (CAT# PABC-462)
    Application: WB, HA, ELISA, FC, Neut

    Figure 2 Mouse Anti-PTPRC Recombinant Antibody (HPAB-0258-FY) in HPLC

    Mouse Anti-PTPRC Recombinant Antibody (HPAB-0258-FY) (CAT# HPAB-0258-FY)
    Application: ELISA

    Figure 3 Mouse Anti-ανβ8 Recombinant Antibody (HPAB-N0303-YC) in ELISA

    Mouse Anti-ανβ8 Recombinant Antibody (HPAB-N0303-YC) (CAT# HPAB-N0303-YC)
    Application: ELISA, Block

    Figure 3 Human Anti-IL18 Recombinant Antibody (clone h18-108); scFv Fragment (FAMAB-0041JF-S(P)) in ELISA

    Human Anti-IL18 Recombinant Antibody (clone h18-108); scFv Fragment (CAT# FAMAB-0041JF-S(P))
    Application: IB, FC, ELISA, FuncS

    Figure 2 Mouse Anti-MUC16 Recombinant Antibody (ZG-0056J) in IHC

    Mouse Anti-MUC16 Recombinant Antibody (ZG-0056J) (CAT# ZG-0056J)
    Application: IHC-P, IF

    Figure 4 Mouse Anti-HA-Tag Antibody (ZG-0285U) in FC

    Mouse Anti-HA-Tag Recombinant Antibody (clone 18B11H6) (CAT# ZG-0285U)
    Application: ELISA, WB, IF, FC, IP

    Figure 3 Mouse Anti-E-Tag Antibody (ZG-0287U) in ELISA

    Mouse Anti-E-Tag Recombinant Antibody (clone 11H12B3) (CAT# ZG-0287U)
    Application: ELISA, WB, IP

    For Research Use Only. Not For Clinical Use.

    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

    Send Inquiry

    This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

    Go to compare

    Go to compare