Recombinant Anti-human NUP88 Intrabody [Tat] (CAT#: IAB-B063(T))

Recombinant anti-NUP88 intrabody in fusion with HIV Tat works within cells to bind the nuclear pore protein NUP88, expressed in E. coli cells. Anti-Nup88 intrabody, an anti-sense oligonucleotide or nucleic acid which is complementary to at least a functional part of a Nup88 RNA or wherein the compound is a peptide, peptide-like or non-peptide Nup88 inhibitor which can be identified by contacting the compound or libraries of peptido- mimetics, peptides, DNA or cDNA expression, combinatorial chemistry or phage display with substantially purified Nup88, fragments thereof or structural analogues thereof.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • human nucleoporin 88kDa
  • Host Species
  • rabbit
  • Type
  • scFv-Tat
  • Cell Penetrating Peptide
  • TAT
    TAT was able to deliver different proteins, such as horseradish peroxidase and RNase A across cell membrane into the cytoplasm in different cell lines in vitro. The size range of proteins with effective delivery is from 30kDa to 120-150kDa. In one study, TAT-fused proteins are rapidly internalized by lipid raft−dependent macropinocytosis using a transducible TAT−Cre recombinase reporter assay on live cells. In another study, a TAT-fused protein was delivered into mitochondria of breast cancer cells and decreased the survival of breast cancer cells, which showed capability of TAT-fusion proteins to modulate mitochondrial function and cell survival. However, very few in vivo studies have succeeded. In one study, in vivo delivery of TAT- or penetratin-crosslinked Fab fragments yielded varied organ distributions and an overall increase in organ retention, which showed tissue localization.
  • Species Reactivity
  • human
  • Applications
  • Antibody assay: Enzyme-linked Immunosorbent Assay; Immunofluorescence; Neutralization; Functional studies

Product Property

  • Purity
  • 95% by HPLC
  • Storage
  • Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.

Target

  • Alternative Names
  • NUP88; nucleoporin 88kDa; nuclear pore complex protein Nup88; karyoporin; nucleoporin 88kD; nucleoporin Nup88; 88 kDa nucleoporin; nuclear pore complex protein 88

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "NUP88"

Recombinant Antibody

CAT Product Name Application Type
MOB-2733z Mouse Anti-NUP88 Recombinant Antibody (clone 39C9) WB, ELISA, IF, IP Mouse IgG2b, κ

Intrabody

CAT Product Name Application Type
IAB-B063(A) Recombinant Anti-human NUP88 Intrabody [(D-Arg)9] ELISA, Neut, FuncS scFv-(D-Arg)9
IAB-B063(G) Recombinant Anti-human NUP88 Intrabody [+36 GFP] PCA, WB, FuncS scFv-(+36GFP)

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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