Anti-Human ORAI1 Antibody, Research Grade Biosimilar
CAT#: TAB-756CL
Recombinant Human monoclonal antibody expressed in CHO binding to Human ORAI1. The antibody specifically binds to human Orai1. We use it in treating immune disorder or disease, such as graft versus host disease (GVHD), rheumatoid arthritis, multiple sclerosis.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human skin
Immunohistochemical staining of human skin shows membranous positivity in squamous epithelial cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16583/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16583/37073_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16583/37073_A_8_3.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16583/37073_A_6_6.jpg
Normal Tissue
Figure 5 Skin
Epidermal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16583/37073_B_5_8.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (NB-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000276045-ORAI1
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Specifications
- Host Species
- Human
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- Immune Disorder or Disease
Product Property
- Purity
- 95% by HPLC
- Storage
- Short Term Storage: 4°C
Long Term Storage: -20°C
Target
- Alternative Names
- ORAI1; ORAI calcium release-activated calcium modulator 1; IMD9; TAM2; ORAT1; CRACM1; TMEM142A; calcium release-activated calcium channel protein 1; protein orai-1; transmembrane protein 142A; calcium release-activated calcium modulator 1
- Gene ID
- 84876
- UniProt ID
- A0A024RBT3
REVIEWS AND Q&AS
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Strong Binding To ORAI1
This recombinant human monoclonal antibody showed excellent binding affinity to Human ORAI1 in our lab tests. We are investigating calcium release-activated channels, and this reagent has been a key tool for identifying the receptor expression.
Consistent HPLC Purity
We verified the purity of this product upon receipt and found it matched the 95 percent specification by HPLC. The consistency between batches has been reliable, which is crucial for our ongoing research into immune disorder mechanisms.
Q&As
-
What is the target specificity of this antibody?
A: This Recombinant Human monoclonal antibody specifically binds to Human ORAI1 (calcium release-activated calcium modulator 1). It is designed for research into immune disorders and diseases such as graft versus host disease and rheumatoid arthritis.
-
Is this antibody monoclonal or polyclonal?
A: This is a Recombinant Human monoclonal antibody expressed in Chinese Hamster Ovary (CHO) cells. It is produced with high purity (95% by HPLC) to ensure consistent binding to the human Orai1 protein in your experiments.
View the frequently asked questions answered by Creative Biolabs Support.
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Related Diseases
Primary Immunodeficiency
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
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| TAB-0853CL | Human Anti-ORAI1 Recombinant Antibody (TAB-0853CL) | FC, Inhib | Chimeric (rat/human) IgG |
| CAT | Product Name | Application | Type |
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| TAB-0854CL | Human Anti-ORAI1 Recombinant Antibody (TAB-0854CL) | FC, Inhib | Chimeric (rat/human) IgG |
| CAT | Product Name | Application | Type |
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| TAB-0855CL | Mouse Anti-ORAI1 Recombinant Antibody (TAB-0855CL) | FuncS, FC, WB, Inhib | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0856CL | Mouse Anti-ORAI1 Recombinant Antibody (TAB-0856CL) | FuncS, FC, WB, Inhib | Mouse IgG |
| CAT | Product Name | Application | Type |
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| TAB-0857CL | Mouse Anti-ORAI1 Recombinant Antibody (TAB-0857CL) | FuncS, FC, WB, Inhib | Mouse IgG |
| CAT | Product Name | Application | Type |
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| TAB-0853CL-S(P) | Rat Anti-ORAI1 Recombinant Antibody; scFv Fragment (TAB-0853CL-S(P)) | FC | scFv |
| CAT | Product Name | Application | Type |
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| TAB-0854CL-S(P) | Rat Anti-ORAI1 Recombinant Antibody; scFv Fragment (TAB-0854CL-S(P)) | FC | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0853CL-F(E) | Human Anti-ORAI1 Recombinant Antibody; Fab Fragment (TAB-0853CL-F(E)) | FC | Chimeric (rat/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2550 | Hi-Affi™ Recombinant Rabbit Anti-ORAI1 Monoclonal Antibody (DS2550AB) | WB | IgG |
| CAT | Product Name | Application | Type |
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| MRO-2096-CN | Rabbit Anti-ORAI1 Polyclonal Antibody (MRO-2096-CN) | WB, IF, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| HPAB-0508-FY | Mouse Anti-ORAI1 Recombinant Antibody (HPAB-0508-FY) | ELISA, Inhib, Block, FuncS | Mouse IgG |
| CAT | Product Name | Application | Type |
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| HPAB-0509-FY | Mouse Anti-ORAI1 Recombinant Antibody (HPAB-0509-FY) | ELISA, Block, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
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| HPAB-0508-FY-S(P) | Mouse Anti-ORAI1 Recombinant Antibody; scFv Fragment (HPAB-0508-FY-S(P)) | ELISA, Inhib | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0509-FY-S(P) | Mouse Anti-ORAI1 Recombinant Antibody; scFv Fragment (HPAB-0509-FY-S(P)) | ELISA, Inhib | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0508-FY-F(E) | Mouse Anti-ORAI1 Recombinant Antibody; Fab Fragment (HPAB-0508-FY-F(E)) | ELISA, Inhib | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0509-FY-F(E) | Mouse Anti-ORAI1 Recombinant Antibody; Fab Fragment (HPAB-0509-FY-F(E)) | ELISA, Inhib | Mouse Fab |
| CAT | Product Name | Application | Type |
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| VS13-YC861 | Rabbit Anti-ORAI1 Recombinant Antibody (VS13-YC861) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| VS-0425-YC293 | Recombinant Anti-ORAI1 Vesicular Antibody, EV Displayed (VS-0425-YC293) | ELISA, FC, Inhib, Cell-uptake |
| CAT | Product Name | Application | Type |
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| VS-0525-XY5097 | Anti-ORAI1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
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| VS-0525-XY5098 | Anti-Mouse ORAI1 Immunohistochemistry Kit | IHC |
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