Recombinant Mouse Anti-P-glycoprotein Antibody (C219) (CAT#: PABC-102)

Recombinant Mouse Antibody (C219) is capable of binding to P-glycoprotein, expressed in Chinese Hamster Ovary cells (CHO).


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Datasheet
  • MSDS
  • COA
WB

Figure 1 Immunoblot analysis of P-glycoprotein expression in plasma membrane.

Figure 1 Immunoblot analysis of P-glycoprotein expression in plasma membrane.

Membrane vesicle preparation (10 mg) was added to each lane, and after incubation with the primary antibody (C219) and appropriate washes, the blot was exposed to a standardKodak X-omat AR film for 15 s.

Kim, R. B. , Fromm, M. F. , Wandel, C. , Leake, B. , & Wilkinson, G. R.. (1998). The drug transporter p-glycoprotein limits oral absorption and brain entry of hiv-1 protease inhibitors. Journal of Clinical Investigation, 101(2), 289-294.


Specifications

  • Immunogen
  • P-glycoprotein
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • IgG
  • Specificity
  • Tested positive against native P-glycoprotein
  • Clone
  • C219
  • Applications
  • WB

Product Property

  • Purity
  • >95% by SDS-PAGE and HPLC analysis
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Applications

  • Application Notes
  • The antibody C219 has been reported in applications of Western Blot. It's recommended that the optimal antibody concentration, dilution, incubition time etc. be carefully titrated in specific assays.

Target

  • Alternative Names
  • P-glycoprotein 1; permeability glycoprotein; P-gp; Pgp; multidrug resistance protein 1; MDR1; ATP-binding cassette sub-family B member 1; ABCB1; cluster of differentiation 243; CD243

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone C219"

See other products for "P-gp"

Recombinant Antibody

CAT Product Name Application Type
PABZ-102 Recombinant Mouse Anti-P-glycoprotein Antibody (MRK-16) WB, IHC, IF, FuncS IgG

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for PABC-102. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare