Anti-Human PTN Recombinant Antibody Fab Fragment (4B2) (CAT#: TAB-290CT-F(E))
Recombinant monoclonal antibody can specifically bind to the human PTN. It neutralizes at least one biological activity of pleiotrophin. The antibodies can inhibit cancer cell growth and angiogenesis in vitro or in vivo.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line AF22
(Immunofluorescent staining of human cell line AF22 shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73913/1783_H10_4_selected.jpg
(Immunofluorescent staining of human cell line AF22 shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73913/1783_H10_4_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17685/164389_B_8_5.jpg
(Neuronal cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17685/164389_B_8_5.jpg
Figure 3 Testis
(Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17685/164396_A_6_6.jpg
(Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17685/164396_A_6_6.jpg
Figure 4 RNA cell line category: Cell line enriched (AF22)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105894-PTN/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105894-PTN/subcellular
Specifications
- Immunogen
- Human pleiotrophin fused with human Fc
- Host Species
- Mouse
- Derivation
- Mouse hybridoma cell lines
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- 4B2
- Applications
- Used for immunoassay techniques such as: Western Blot; Enzyme-linked Immunosorbent Assay; Immunohistochemistry; Neutralization
- Related Disease
- Prostatic neoplastic diseases, prostate carcinoma
Target
- Alternative Names
- PTN; pleiotrophin; HARP; HBNF; HBGF8; NEGF1; HBBM; OSF-1; HB-GAM; HBGF-8; HBNF-1; osteoblast-specific factor 1; heparin-binding brain mitogen; heparin binding growth factor 8; heparin-binding growth factor 8; heparin affin regulatory protein; neurite growth-promoting factor 1; heparin-binding growth-associated molecule; heparin-binding neurite outgrowth-promoting factor 1; pleiotrophin (heparin binding growth factor 8; neurite growth-promoting factor 1); anti-PTN
- Gene ID
- 5764
- UniProt ID
- A0A024R778
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Mouse Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2000z | Mouse Anti-PTN Recombinant Antibody (clone 39C3) | WB, FC, IF, IHC, IP | Mouse IgG1, κ |
| MOB-1271CT | Recombinant Mouse anti-Human PTN Monoclonal antibody (EML653) | IHC-P, WB | |
| VS3-FY1223 | Recombinant Rabbit Anti-PTN Antibody (clone R01-2J3) | WB, IP | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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