Anti-Human PTPRB Antibody, Research Grade Biosimilar (CAT#: TAB-722CL)
Recombinant Rabbit monoclonal antibody expressed in CHO binding to Human PTPRB. This antibody is expected to recognize both reported isoforms of protein tyrosine phosphatase, receptor type, beta polypeptide (PTPRB), which is critical in physiological and pathological events such as cell migration, adhesion and transformation.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67868/1717_A6_22_cr57f514fc87452_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67868/1717_A6_22_cr57f514fc87452_selected.jpg
Figure 2 IHC staining of human prostate
(Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4782/ihc_selected.jpg
(Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4782/ihc_selected.jpg
Figure 3 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67868/1315_H7_2_blue_red_green.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67868/1315_H7_2_blue_red_green.jpg
Figure 4 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67868/1287_H7_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67868/1287_H7_1_blue_red_green.jpg
Figure 5 Cerebral cortex
(Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4782/11835_B_8_5.jpg
(Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4782/11835_B_8_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4782/11671_A_6_6.jpg
(Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4782/11671_A_6_6.jpg
Figure 7 Lymph node
(Germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4782/11671_A_9_8.jpg
(Germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4782/11671_A_9_8.jpg
Figure 8 RNA cell line category: Cell line enhanced (EFO-21, hTERT-RPE1, HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000127329-PTPRB
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000127329-PTPRB
Specifications
- Host Species
- Rabbit
- Derivation
- Rabbit
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- Diabetic macular edema
Product Property
- Purity
- >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
- Storage
- Short Term Storage: 4°C
Long Term Storage: -20°C
Target
- Alternative Names
- PTPRB; protein tyrosine phosphatase, receptor type, B; PTPB; HPTPB; VEPTP; HPTP-BETA; R-PTP-BETA; receptor-type tyrosine-protein phosphatase beta; VE-PTP; vascular endothelial protein tyrosine phosphatase; protein tyrosine phosphatase, receptor type, beta
- Gene ID
- 5787
- UniProt ID
- P23467
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Human Antibody Products
IgM Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3104z | Mouse Anti-PTPRB Recombinant Antibody (clone 7C10) | ICC, IF | Mouse IgG2a |
| MRO-1296-CN | Recombinant Mouse Anti-PTPRB Monoclonal Antibody (2-A2) | IF, IHC | Mouse IgG2a |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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