Recombinant Human Anti-S. aureus Hla Antibody scFv Fragment (MEDI4893)
CAT#: PSBL-395
Recombinant Human Antibody (MEDI4893) scFv Fragment is specific to S. aureus Hla, expressed in E. coli. This scFv fragment recognizes a novel epitope in the so-called "rim" domain of AT and exerts its neutralizing effect through a dual mechanism. In particular, it not only sterically blocks binding of AT to its cell receptor but also prevents it from adopting a lytic heptameric trans-membrane conformation.
Specifications
- Immunogen
- S. aureus alpha-hemolysin
- Host Species
- Human
- Derivation
- Human
- Type
- scFv
- Specificity
- Tested positive against native S. aureus Hla
- Species Reactivity
- S. aureus
- Clone
- MEDI4893
- Applications
- Can be useful in applications such as: Blocking
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- Hla; alpha-hemolysin; Alpha-toxin; Staphylococcus aureus alpha toxin
- Gene ID
- 28793
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
See other products for "Clone MEDI4893"
- CAT
- Product Name
See other products for "Hla"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-358CL | Anti-Human Hla Recombinant Antibody (TAB-358CL) | FuncS, Neut | Antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-332 | Recombinant Human Anti-S.Aureus a-hemolysin Antibody | WB, ELISA, IF, FuncS | IgG |
PABL-396 | Recombinant Human Anti-S. aureus Hla Antibody (MEDI4893) | BL | IgG |
PABL-696 | Recombinant Human Anti-S. aureus a-hemolysin Antibody | WB, IHC, IF, FuncS | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-332 | Recombinant Human Anti-S.Aureus a-hemolysin Antibody scFv Fragment | WB, ELISA, IF, FuncS | scFv |
PSBL-689 | Recombinant Human Anti-S. aureus a-hemolysin Antibody scFv Fragment | WB, IHC, IF, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-332 | Recombinant Human Anti-S.Aureus a-hemolysin Antibody Fab Fragment | WB, ELISA, IF, FuncS | Fab |
PFBL-395 | Recombinant Human Anti-S. aureus Hla Antibody Fab Fragment (MEDI4893) | BL | Fab |
PFBL-689 | Recombinant Human Anti-S. aureus a-hemolysin Antibody Fab Fragment | WB, IHC, IF, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0325-FY151 | Human Anti-hla (clone MEDI4893) scFv-Fc Chimera | ELISA | Human IgG1, scFv-Fc |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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