Recombinant Human Anti-S. aureus Hla Antibody scFv Fragment (MEDI4893) (CAT#: PSBL-395)
Recombinant Human Antibody (MEDI4893) scFv Fragment is specific to S. aureus Hla, expressed in E. coli. This scFv fragment recognizes a novel epitope in the so-called "rim" domain of AT and exerts its neutralizing effect through a dual mechanism. In particular, it not only sterically blocks binding of AT to its cell receptor but also prevents it from adopting a lytic heptameric trans-membrane conformation.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Specifications
- Immunogen
- S. aureus alpha-hemolysin
- Host Species
- Human
- Derivation
- Human
- Type
- scFv
- Specificity
- Tested positive against native S. aureus Hla
- Species Reactivity
- S. aureus
- Clone
- MEDI4893
- Applications
- Can be useful in applications such as: Blocking
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- Hla; alpha-hemolysin; Alpha-toxin; Staphylococcus aureus alpha toxin
- Gene ID
- 28793
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Human Antibody Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-358CL | Anti-Human Hla Recombinant Antibody (TAB-358CL) | FuncS, Neut | Antibody |
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