Recombinant Human Anti-S. aureus Hla Antibody scFv Fragment (MEDI4893) (CAT#: PSBL-395)
Recombinant Human Antibody (MEDI4893) scFv Fragment is specific to S. aureus Hla, expressed in E. coli. This scFv fragment recognizes a novel epitope in the so-called "rim" domain of AT and exerts its neutralizing effect through a dual mechanism. In particular, it not only sterically blocks binding of AT to its cell receptor but also prevents it from adopting a lytic heptameric trans-membrane conformation.
Specific Inquiry
Specifications
- Immunogen
- S. aureus alpha-hemolysin
- Host Species
- Human
- Derivation
- Human
- Type
- scFv
- Specificity
- Tested positive against native S. aureus Hla
- Species Reactivity
- S. aureus
- Clone
- MEDI4893
- Applications
- Can be useful in applications such as: Blocking
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- Hla; alpha-hemolysin; Alpha-toxin; Staphylococcus aureus alpha toxin
- Gene ID
- 28793
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-358CL | Anti-Human Hla Recombinant Antibody (TAB-358CL) | FuncS, Neut | Antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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