Anti-Human SCN9A Recombinant Antibody, Humanized
CAT#: TAB-551CL
Recombinant Humanized monoclonal antibody expressed in CHO binding to Human SCN9A. This is a monoclonal antibody that targets a NaV1. 7 channel voltage sensor, can be used for pain and itch relief.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line BJ
Immunofluorescent staining of human cell line BJ shows localization to plasma membrane, actin filaments & focal adhesion sites.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/61843/1332_D6_5_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human colon
Immunohistochemical staining of human colon shows cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_7_3_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Glial cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_7_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_9_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_6_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13679/30465_A_7_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, HHSteC, hTERT-RPE1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169432-SCN9A/subcellular
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Specifications
- Derivation
- Humanized
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- Pain
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- ≤1 year at -20°C.
Target
- Alternative Names
- SCN9A; sodium channel, voltage gated, type IX alpha subunit; PN1; ETHA; NENA; SFNP; FEB3B; NE-NA; GEFSP7; HSAN2D; Nav1.7; sodium channel protein type 9 subunit alpha; hNE-Na; peripheral sodium channel 1; neuroendocrine sodium channel; sodium channel prote
- Gene ID
- 6335
- UniProt ID
- Q15858
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "SCN9A"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-891 | Recombinant Anti-human SCN9A Antibody | WB, FC, FuncS | IgG |
| MHH-891 | Recombinant Human Anti-human SCN9A Antibody | WB, Neut, FuncS | IgG |
| HPAB-0052-FY | Rabbit Anti-SCN9A Recombinant Antibody (HPAB-0052-FY) | ELISA | Rabbit IgG1 |
| MRO-1062-CN | Recombinant Mouse Anti-SCN9A Monoclonal Antibody (1D6) | IHC, IF, FC, WB | Mouse IgG2b |
| HPAB-0109-WJ | Human Anti-SCN9A Recombinant Antibody (HPAB-0109-WJ) | ELISA | Human IgG4, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-891-F(E) | Recombinant Anti-human SCN9A Antibody Fab Fragment | ELISA, RIA, FuncS | Fab |
| MHH-891-F(E) | Recombinant Human Anti-human SCN9A Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
| HPAB-0109-WJ-F(E) | Human Anti-SCN9A Recombinant Antibody (HPAB-0109-WJ-F(E)); Fab Fragment | ELISA | Human Fab |
| HPAB-0542-FY-F(E) | Human Anti-SCN9A Recombinant Antibody (clone 22D04); Fab Fragment | ELISA | Human Fab |
| HPAB-0543-FY-F(E) | Human Anti-SCN9A Recombinant Antibody (clone 28608); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-891-S(P) | Recombinant Anti-human SCN9A Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
| MHH-891-S(P) | Recombinant Human Anti-human SCN9A Antibody scFv Fragment | WB, IHC, FuncS | scFv |
| HPAB-0052-FY-S(P) | Rabbit Anti-SCN9A Recombinant Antibody; scFv Fragment (HPAB-0052-FY-S(P)) | ELISA | Rabbit scFv |
| HPAB-0109-WJ-S(P) | Human Anti-SCN9A Recombinant Antibody (HPAB-0109-WJ-S(P)); scFv Fragment | ELISA | Human scFv |
| HPAB-0542-FY-S(P) | Human Anti-SCN9A Recombinant Antibody (clone 22D04); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0334CL | Human Anti-SCN9A Recombinant Antibody (TAB-0334CL) | FuncS, IHC, Block, Inhib, ELISA | Human IgG |
| TAB-0334CL-S(P) | Human Anti-SCN9A Recombinant Antibody; scFv Fragment (TAB-0334CL-S(P)) | FuncS, IHC, Block, Inhib, ELISA | Human scFv |
| TAB-0334CL-F(E) | Human Anti-SCN9A Recombinant Antibody; Fab Fragment (TAB-0334CL-F(E)) | FuncS, IHC, Block, Inhib, ELISA | Human Fab |
| TAB-474MZ | Human Anti-SCN9A Recombinant Antibody (TAB-474MZ) | ELISA | Human IgG |
| TAB-475MZ | Human Anti-SCN9A Recombinant Antibody (TAB-475MZ) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-469MZ | Anti-Human SCN9A Recombinant Antibody (8A7) | ELISA, FuncS | |
| TAB-470MZ | Anti-Human SCN9A Recombinant Antibody (8B6) | ELISA | |
| TAB-471MZ | Anti-Human SCN9A Recombinant Antibody (9A1) | ELISA | |
| TAB-472MZ | Anti-Human SCN9A Recombinant Antibody (9A6) | ELISA | |
| TAB-473MZ | Anti-Human SCN9A Recombinant Antibody (9A11) | ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-053CN | Mouse Anti-SCN9A Recombinant Antibody (NS-053CN) | ELISA, Block, FuncS | Mouse IgG1 |
| NS-053CN-F(E) | Mouse Anti-SCN9A Recombinant Antibody; Fab Fragment (NS-053CN-F(E)) | ELISA | Mouse Fab |
| NS-053CN-S(P) | Mouse Anti-SCN9A Recombinant Antibody; scFv Fragment (NS-053CN-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC655 | Recombinant Anti-SCN9A Vesicular Antibody, EV Displayed (VS-0425-YC655) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6390 | Anti-SCN9A Immunohistochemistry Kit | IHC |
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