Anti-Human SCN9A Recombinant Antibody (8A7) (CAT#: TAB-469MZ)
This antibody 8A7 binds to ion channels, in particular the voltage-gated sodium channel Nav1.7. The antibody was generated by DNA immunization.
Specific Inquiry
ELISA
Figure 1 shows the specificity of binding to either Navl.7 extracellular loop A3, extracellular loop B 1-C1-D1 or extracellular loop C3 for Navl.7 antibodies derived by DNA immunization.
ELISA
Figure 2 shows the binding affinity for human Navl.7 extracellular loop A3 of Navl.7 antibodies raised by DNA immunization, as measured by ELISA.
FuncS
Figure 3 shows the results of functional characterization of mAb 8A7 using manual patch clamp electrophysiology.
Voltage/current density curve.
Specifications
- Immunogen
- DNA immunization
- Host Species
- Llama
- Derivation
- Library
- Specificity
- Human
- Clone
- 8A7
- Applications
- ELISA, FuncS
- Related Disease
- Neuropathic pain
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Functional Assay.
Target
- Alternative Names
- SCN9A; sodium channel, voltage gated, type IX alpha subunit; PN1; ETHA; NENA; SFNP; FEB3B; NE-NA; GEFSP7; HSAN2D; Nav1.7; sodium channel protein type 9 subunit alpha; hNE-Na; peripheral sodium channel 1; neuroendocrine sodium channel; sodium channel protein type IX subunit alpha; voltage-gated sodium channel alpha subunit Nav1.7; voltage-gated sodium channel subunit alpha Nav1.7; sodium channel, voltage-gated, type IX, alpha subunit; sodium channel, voltage-gated, type IX, alpha polypeptide
- Gene ID
- 6335
- UniProt ID
- Q15858
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-891-F(E) | Recombinant Anti-human SCN9A Antibody Fab Fragment | ELISA, RIA, FuncS | Fab |
| MHH-891-F(E) | Recombinant Human Anti-human SCN9A Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
| HPAB-0109-WJ-F(E) | Human Anti-SCN9A Recombinant Antibody (HPAB-0109-WJ-F(E)); Fab Fragment | ELISA | Human Fab |
| HPAB-0542-FY-F(E) | Human Anti-SCN9A Recombinant Antibody (clone 22D04); Fab Fragment | ELISA | Human Fab |
| HPAB-0543-FY-F(E) | Human Anti-SCN9A Recombinant Antibody (clone 28608); Fab Fragment | ELISA | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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