This product is a recombinant humanized antibody that recognizes SEMA4D. The antibody was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography. The antibody was able to block the interaction of soluble CD100 with its receptor in activated T cells, and prevented the apoptosis of oligodendrocytes in HTLV-1 associated disease. The antibody is IgA, recognize the human form of the CD100 semaphorin via conformational epitopes. The mAb induces release of CD100 and dissociates the CD100-kinase complexes. It is co-mitogenic with CD2 and CD3.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-559CL | Human Anti-SEMA4D Recombinant Antibody (TAB-559CL) | ELISA | Human IgG |
TAB-430CT | Humanized Anti-SEMA4D Recombinant Antibody (TAB-430CT) | WB | Humanized IgG |
TAB-429CT-S(P) | Humanized Anti-SEMA4D Recombinant Antibody; scFv Fragment (TAB-429CT-S(P)) | WB, ELISA, FC, BL | Humanized scFv |
TAB-429CT-F(E) | Humanized Anti-SEMA4D Recombinant Antibody; Fab Fragment (TAB-429CT-F(E)) | WB, ELISA, FC, BL | Humanized Fab |
TAB-430CT-F(E) | Humanized Anti-SEMA4D Recombinant Antibody; Fab Fragment (TAB-430CT-F(E)) | WB, ELISA, FC, BL | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3206 | Hi-Affi™ Recombinant Rabbit Anti-SEMA4D Monoclonal Antibody (DS3206AB) | WB, IHC, ICC | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0049-WJ | Mouse Anti-SEMA4D Recombinant Antibody (HPAB-0049-WJ) | FC, ELISA, IHC, FuncS, Inhib | Mouse IgG1 |
HPAB-AP440-YC | Mouse Anti-SEMA4D Recombinant Antibody (HPAB-AP440-YC) | ELISA, Block, Neut, FuncS | Mouse IgG2b |
HPAB-AP442-YC | Mouse Anti-SEMA4D Recombinant Antibody (HPAB-AP442-YC) | ELISA, Block, Neut, FuncS | Mouse IgG2b |
HPAB-AP443-YC | Human Anti-SEMA4D Recombinant Antibody (HPAB-AP443-YC) | ELISA, FC, Block | Human IgG1 |
ZG-0137U | Human Anti-SEMA4D Recombinant Antibody (clone 21E8) | ELISA, FC | Humanized IgG4 |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0049-WJ-S(P) | Mouse Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-0049-WJ-S(P)) | FC, ELISA | Mouse scFv |
HPAB-AP440-YC-S(P) | Mouse Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-AP440-YC-S(P)) | ELISA, Block, Neut, FuncS | Mouse scFv |
HPAB-AP442-YC-S(P) | Mouse Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-AP442-YC-S(P)) | ELISA, Block, Neut, FuncS | Mouse scFv |
HPAB-AP443-YC-S(P) | Human Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-AP443-YC-S(P)) | ELISA, FC, Block | Human scFv |
HPAB-AP444-YC-S(P) | Human Anti-SEMA4D Recombinant Antibody; scFv Fragment (HPAB-AP444-YC-S(P)) | ELISA, FC, Block | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-AP440-YC-F(E) | Mouse Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP440-YC-F(E)) | ELISA, Block, Neut, FuncS | Mouse Fab |
HPAB-AP442-YC-F(E) | Mouse Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP442-YC-F(E)) | ELISA, Block, Neut, FuncS | Mouse Fab |
HPAB-AP443-YC-F(E) | Human Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP443-YC-F(E)) | ELISA, FC, Block | Human Fab |
HPAB-AP444-YC-F(E) | Human Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP444-YC-F(E)) | ELISA, FC, Block | Human Fab |
HPAB-AP445-YC-F(E) | Human Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP445-YC-F(E)) | ELISA, Block | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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