Anti-Human SERPINA5 Recombinant Antibody (PC23A7) (CAT#: TAB-0947CL)
This antibody (PC23A7) has protein C inhibitor (PCI)-neutralizing activity and inhibits PCI's inhibitory effect on the production and activity of activated protein C (aPC). It also can be used to maintain aPC activity and sustain the effects of aPC physiological activities, such as suppression of the activation of blood coagulation system and anti-inflammatory functions. PC23A7 is an IgG2a and exhibited strong PCI-neutralizing activity by aPC/PCI assay using the purified antibody. The KD value is 0.473 nM.
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Normal Tissue
RNA Expression
Figure 1 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/78846/169300_A_9_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/78846/169300_A_9_3.jpg
Figure 2 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/78846/169300_A_8_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/78846/169300_A_8_4.jpg
Figure 3 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/78846/169300_A_8_5.jpg
(Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/78846/169300_A_8_5.jpg
Figure 4 High expression in testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/78846/169300_A_6_6.jpg
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/78846/169300_A_6_6.jpg
Figure 5 RNA cell line category: Cell line enriched (Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000188488-SERPINA5
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000188488-SERPINA5
Specifications
- Immunogen
- PCI-Flag
- Host Species
- Mouse
- Specificity
- Human
- Clone
- PC23A7
- Applications
- SDS-PAGE, WB
- Related Disease
- Thrombosis, sepsis
Target
- Alternative Names
- SERPINA5; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5; PCI; PAI3; PAI-3; PCI-B; PROCI; PLANH3; plasma serine protease inhibitor; protein C inhibitor; plasminogen activator inhibitor-3; acrosomal serine protease inhibitor; plasminogen activator inhibitor III; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
- Gene ID
- 5104
- UniProt ID
- A0A024R6N9
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Mouse Antibody Products
Rabbit Monoclonal Antibody Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0946CL | Anti-Human SERPINA5 Recombinant Antibody (PC31E2) | SDS-PAGE, WB | |
| TAB-0946CL-S(P) | Anti-Human SERPINA5 Recombinant Antibody scFv Fragment (PC31E2) | SDS-PAGE, WB | |
| TAB-0947CL-S(P) | Anti-Human SERPINA5 Recombinant Antibody scFv Fragment (PC23A7) | SDS-PAGE, WB | |
| TAB-0946CL-F(E) | Anti-Human SERPINA5 Recombinant Antibody Fab Fragment (PC31E2) | SDS-PAGE, WB | |
| TAB-0947CL-F(E) | Anti-Human SERPINA5 Recombinant Antibody Fab Fragment (PC23A7) | SDS-PAGE, WB |
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