Anti-Human SERPINE1 Recombinant Antibody

CAT#: TAB-562CL

Recombinant Human monoclonal antibody expressed in CHO binding to Human SERPINE1. The antibody molecules which bind plasminogen activator inhibitor 1 (PAI-1) are useful for treating diseases and conditions caused or exacerbated by fibrosis, such as systemic lupus erythromatosus (SLE), scleroderma, pulmonary fibrosis (wherein the disease is not idiopathic pulmonary fibrosis (IPF)), diabetic nephropathy, lupus nephritis, graft versus host disease, glomerulonephritis, focal segmental glomerulosclerosis, membranous nephropathy, mesangial proliferative glomerulonephritis, membranoproliferative glomerulonephritis, renal fibrosis, and COPD.

Gene Expression
Figure 1 IF staining of human cell line U-251 MG Figure 2 IHC staining of human placenta Figure 3 IF staining of human cell line U-2 OS Figure 4 RNA cell line category: Cell line enhanced (BJ, HUVEC TERT2, LHCN-M2, TIME, U-138 MG, U-251 MG)

Specifications

  • Host Species
  • Human
  • Type
  • Antibody
  • Species Reactivity
  • Human
  • Related Disease
  • SLE; Scleroderma; Diabetic Nephropathy

Product Property

  • Purity
  • >98% by SDS-PAGE and HPLC analysis
  • Storage
  • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

Target

  • Alternative Names
  • SERPINE1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; PAI; PAI1; PAI-1; PLANH1; plasminogen activator inhibitor 1; serpin E1; endothelial plasminogen activator inhibitor; serine (or cysteine) proteinase i
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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