Anti-Human SHH Recombinant Antibody (MEDI-5304) (CAT#: TAB-566CL)
Recombinant Human monoclonal antibody expressed in CHO binding to Human SHH. MEDI-5304 is the first fully human hedgehog antibody which inhibited transcription of hedgehog target genes and osteoblast differentiation of C3H10T1/2 cells. MEDI-5304 represents a potent dual hedgehog inhibitor suitable for continued development to evaluate efficacy and safety in human patients with tumors harboring elevated levels of SHH or IHH.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (EFO-21, GAMG, OE19, RT4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164690-SHH/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164690-SHH/subcellular
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- Antibody
- Species Reactivity
- Human
- Applications
- Inhib
- Related Disease
- Tumors
Product Property
- Purity
- >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
- Storage
- 4 °C, -20°C if preferred
Applications
- Application Notes
- This antibody has been tested for use in Inhibition. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- SHH; sonic hedgehog; TPT; HHG1; HLP3; HPE3; SMMCI; TPTPS; MCOPCB5; sonic hedgehog protein; sonic hedgehog homolog
- Gene ID
- 6469
- UniProt ID
- Q15465
Related Resources
JAK-STAT Signaling Pathway
Pancreatic Cancer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "SHH"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
Neutralizing Antibody Products
Rabbit Monoclonal Antibody Products
Neuroscience Antibody Products
Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-902 | Recombinant Anti-human SHH Antibody | ELISA, WB, Neut, FuncS | IgG |
| HPAB-N0236-YC | Mouse Anti-SHH Recombinant Antibody (HPAB-N0236-YC) | ELISA, FC, WB, FuncS, Inhib, IF | Mouse IgG |
| VS3-XY1420 | Mouse Anti-SHH Recombinant Antibody (clone 5H4) | ELISA, WB, FC, IHC | Mouse IgG1 |
| VS3-XY1421 | Mouse Anti-SHH Recombinant Antibody (clone 8G3) | ELISA, WB | Mouse IgG1 |
| VS3-FY1333 | Recombinant Rabbit Anti-SHH Antibody (clone R06-9H9) | WB, IHC-Fr, IHC-P, ICC, IF | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for TAB-566CL. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, WB
Application: WB, ELISA, FuncS, IB, FC, SPR, Apop
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, FC, IHC, Neut
-1.png)
Application: ELISA
Application: ELISA, Neut
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
