Mouse Anti-SIGLEC6 Recombinant Antibody (clone Mab239-90); Fab Fragment (CAT#: HPAB-0076CQ-F(E))
Recombinant Fab fragment to SIGLEC6. The antibody specifically binds SIGLEC-6 on mast cells. The anti-SIGLEC-6 antibody has an inhibitory effect on human mast cells.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8945/1847_E5_61_selected.jpg
(Immunofluorescent staining of human cell line HEL shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8945/1847_E5_61_selected.jpg
Figure 2 Colon
(Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18198/148852_A_7_3.jpg
(Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18198/148852_A_7_3.jpg
Figure 3 Kidney
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18198/148852_A_9_5.jpg
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18198/148852_A_9_5.jpg
Figure 4 Placenta
(Syncytiotrophoblasts - cell body
Staining: High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining: Low
Intensity: Weak)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18198/148852_A_2_7.jpg
(Syncytiotrophoblasts - cell body
Staining: High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining: Low
Intensity: Weak)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18198/148852_A_2_7.jpg
Figure 5 RNA cell line category: Cell line enriched (HMC-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105492-SIGLEC6/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105492-SIGLEC6/subcellular
Specifications
- Immunogen
- Human SIGLEC-6
- Host Species
- Mouse
- Type
- Mouse Fab, κ
- Specificity
- Human SIGLEC6
- Species Reactivity
- Human
- Clone
- Mab239-90
- Applications
- ELISA, FuncS, Inhib
- Related Disease
- Asthma
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone Mab239-90"
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-906 | Recombinant Anti-human SIGLEC6 Antibody | WB, FC, FuncS | IgG |
| MHH-906 | Recombinant Human Anti-human SIGLEC6 Antibody | RIA, IP, FuncS | IgG |
| HPAB-0076CQ | Mouse Anti-SIGLEC6 Recombinant Antibody (clone Mab239-90) | ELISA, FuncS, Inhib | Mouse IgG1, κ |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-906-F(E) | Recombinant Anti-human SIGLEC6 Antibody Fab Fragment | FC, WB, FuncS | Fab |
| MHH-906-F(E) | Recombinant Human Anti-human SIGLEC6 Antibody Fab Fragment | ELISA, WB, Dot, FuncS | Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-906-S(P) | Recombinant Anti-human SIGLEC6 Antibody scFv Fragment | WB, IF, FuncS | scFv |
| MHH-906-S(P) | Recombinant Human Anti-human SIGLEC6 Antibody scFv Fragment | WB, ELISA, IHC, FuncS | scFv |
| HPAB-0076CQ-S(P) | Mouse Anti-SIGLEC6 Recombinant Antibody (clone Mab239-90); scFv Fragment | ELISA, FuncS, Inhib | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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