Recombinant monoclonal antibody to SIRPαV1 and V2. Clone 29-AM4-5 is a humanized antibody that can be potentially used in the treatment of Acute myeloid leukemia (AML).
Figure 1 The binding inhibition by three anti-SIRPa antibody format compounds (AM3-35, AM4-5 and AM4-1) of binding between CD47-Fc and hSIRPα V2 expressed on mouse macrophages.
Figure 2 Inhibition of hCD47-Fc binding to human SIRPα-V2 expressed on the surface of CHO cells in A) the absence or presence of two concentrations of anti-SIRPα Ab AM4-5, and, B).
Escalating concentrations of five anti-SIRPα Fab made by affinity maturation of AM4-5.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
NAB-1201-VHH | Recombinant Anti-Mouse Sirpa VHH Single Domain Antibody | IP, FC, ChiP, Neut | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-453CT | Human Anti-SIRPA Recombinant Antibody (TAB-453CT) | Cyt, IF, FC | Chimeric (mouse/human) IgG4 |
TAB-453CT-S(P) | Human Anti-SIRPA Recombinant Antibody; scFv Fragment (TAB-453CT-S(P)) | WB, ELISA | Human scFv |
TAB-453CT-F(E) | Human Anti-SIRPA Recombinant Antibody; Fab Fragment (TAB-453CT-F(E)) | WB, ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-454CT | Anti-Human SIRPA Recombinant Antibody (AM4-1) | ELISA | Human antibody |
TAB-454CT-S(P) | Anti-Human SIRPA Recombinant Antibody scFv Fragment (AM4-1) | ELISA | Human antibody |
TAB-454CT-F(E) | Anti-Human SIRPA Recombinant Antibody Fab Fragment (AM4-1) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0465MZ | Chicken Anti-PTPNS1 Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1970CQ | Recombinant Rat Anti-Sirpa Antibody (P84) | FC, BL, IF, IHC, IP | IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1971CQ | Recombinant Mouse Anti-Sirpa Antibody (CBL650) | WB, FC, CyTOF, Neut | IgG2b |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4429 | Hi-Affi™ Recombinant Rabbit Anti-SIRPA Monoclonal Antibody (SI522DS) | ELISA | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0023-LSX-S(P) | Human Anti-SIRPA Recombinant Antibody (clone 29-AM4-1); scFv Fragment | ELISA | Humanized scFv |
HPAB-0024-LSX-S(P) | Human Anti-SIRPA Recombinant Antibody (clone 29-AM3-4); scFv Fragment | ELISA | Humanized scFv |
HPAB-0025-LSX-S(P) | Human Anti-SIRPA Recombinant Antibody (clone 29-AM4-5); scFv Fragment | ELISA | Humanized scFv |
HPAB-N0386-YC-S(P) | Human Anti-SIRPA Recombinant Antibody; scFv Fragment (HPAB-N0386-YC-S(P)) | ELISA, FC | Human scFv |
HPAB-N0387-YC-S(P) | Mouse Anti-SIRPA Recombinant Antibody; scFv Fragment (HPAB-N0387-YC-S(P)) | ELISA, FC | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0023-LSX-F(E) | Human Anti-SIRPA Recombinant Antibody (clone 29-AM4-1); Fab Fragment | ELISA | Humanized Fab |
HPAB-N0386-YC-F(E) | Human Anti-SIRPA Recombinant Antibody; Fab Fragment (HPAB-N0386-YC-F(E)) | ELISA, FC | Human Fab |
HPAB-N0387-YC-F(E) | Mouse Anti-SIRPA Recombinant Antibody; Fab Fragment (HPAB-N0387-YC-F(E)) | ELISA, FC | Mouse Fab |
HPAB-N0388-YC-F(E) | Mouse Anti-SIRPA Recombinant Antibody; Fab Fragment (HPAB-N0388-YC-F(E)) | ELISA, FC | Mouse Fab |
HPAB-2559LY-F(E) | Human Anti-SIRPA Recombinant Antibody; Fab Fragment (HPAB-2559LY-F(E)) | Inhib | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-080CN | Human Anti-SIRPA Recombinant Antibody (clone 29-AM3-35) | ELISA, Inhib, FuncS | Human IgG |
NS-080CN-F(E) | Human Anti-SIRPA Recombinant Antibody (clone 29-AM3-35); Fab Fragment | ELISA | Human Fab |
NS-080CN-S(P) | Human Anti-SIRPA Recombinant Antibody (clone 29-AM3-35); scFv Fragment | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-1629CQ | Mouse Anti-SIRPA Recombinant Antibody (clone OX41) | FuncS, IP, WB, ELISA, IF, IHC | Mouse IgG2a |
PABJ-0078 | Human Anti-SIRPA Recombinant Antibody (clone 218) | ELISA | Human IgG |
PABJ-0084 | Human Anti-SIRPA Recombinant Antibody (clone 119) | ELISA, Block | Human IgG |
PABJ-0085 | Human Anti-SIRPA Recombinant Antibody (clone 115) | ELISA | Human IgG |
VS3-FY1336 | Recombinant Rabbit Anti-SIRPA Antibody (clone R04-7G6) | WB | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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