Human Anti-SLPI Recombinant Antibody (clone 9G12) (CAT#: HPAB-0081-CN)
An antibody specifically binds to SLPI acts to neutralize SLPI activity, and can modulate SLPI effects. Antibody 9G12 can inhibit SLPI-Cathepsin G activity in a dose dependent manner.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line EFO-21
(Immunofluorescent staining of human cell line EFO-21 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27774/1829_B9_1_selected.jpg
(Immunofluorescent staining of human cell line EFO-21 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27774/1829_B9_1_selected.jpg
Figure 2 Cervix
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27774/58791_B_7_3.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27774/58791_B_7_3.jpg
Figure 3 RNA cell line category: Cell line enhanced (EFO-21, hTCEpi, OE19, SiHa, THP-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000124107-SLPI/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000124107-SLPI/subcellular
Specifications
- Immunogen
- Recombinant human SLPI
- Host Species
- Human
- Derivation
- Human
- Type
- Human IgG2
- Specificity
- Human SLPI
- Species Reactivity
- Human
- Clone
- 9G12
- Applications
- Neut, WB, ELISA, FC, IHC
- Related Disease
- Disease associated with SLPI activity
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- SLPI; secretory leukocyte peptidase inhibitor; ALP; MPI; ALK1; BLPI; HUSI; WAP4; WFDC4; HUSI-I; antileukoproteinase; HUSI-1; protease inhibitor WAP4; mucus proteinase inhibitor; seminal proteinase inhibitor; WAP four-disulfide core domain protein 4; secretory leukocyte protease inhibitor (antileukoproteinase)
- Gene ID
- 6590
- UniProt ID
- P03973
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-911 | Recombinant Anti-human SLPI Antibody | ELISA, IP, FuncS | IgG |
| MHH-911 | Recombinant Human Anti-human SLPI Antibody | ELISA, WB, FuncS | IgG |
| MOB-1583MZ | Recombinant Mouse Anti-Human SLPI Antibody (clone 42) | IHC-Fr, IHC-P, IP, WB | Mouse antibody |
| HPAB-0079-CN | Human Anti-SLPI Recombinant Antibody (clone 43H7) | Neut, WB, ELISA, FC, IHC | Human IgG2 |
| MOB-0804-YJ | Mouse Anti-SLPI Recombinant Antibody (CBS98D) | IHC-Fr, IA, IP, IHC-P, WB | Mouse IgG1 |
Customer Reviews and Q&As
Customer Review
Q&As
Integral for Respiratory Research
The Anti-SLPI Recombinant Antibody provides precise inhibition needed to study respiratory conditions like COPD. Its ability to specifically bind and neutralize SLPI aids significantly in understanding inflammation moderation processes vital for advancing therapeutic strategies.
Empowers Enzyme Activity Studies
By neutralizing SLPI, this antibody helps delineate enzyme activity changes in tissue models, providing new insights into how inflammation affects disease progressions, supported steadily by Creative Biolabs' product quality.
Consistent Performance in Multiple Assays
Performing consistently in ELISA and Western Blot applications, this antibody is a cornerstone for studying SLPI's involvement in diseases of chronic inflammation and immune dysregulation, delivering reliable outcomes.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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