Anti-Human SOST Recombinant Antibody (TAB-115)
CAT#: TAB-115
Recombinant monoclonal antibody to SOST. It binds SOST, a negative regulator of osteoblast activity. Blocking SOST activity can lead to increased bone density.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Group enriched (HaCaT, SuSa)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167941-SOST
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- IgG4 - kappa
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- FuncS, IF, Neut, ELISA, FC, IP, ICC, IO
- MW
- 144.63 kDa
- Related Disease
- Postmenopausal women osteoporosis
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
- Storage
- 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Applications
- Application Notes
- The SOST antibody has been reported in applications of FuncS, IF, Neut, ELISA, FC, IP, ICC, IO.
Target
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Biosimilar Overview
Please refer to Blosozumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Blosozumab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "SOST"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-116 | Human Anti-SOST Recombinant Antibody (TAB-116) | IF, IP, Neut, FuncS, ELISA, FC, ICC | Human IgG2, κ |
| TAB-580CL | Human Anti-SOST Recombinant Antibody (TAB-580CL) | ELISA, WB | Human IgG |
| TAB-411CT-F(E) | Humanized Anti-SOST Recombinant Antibody; Fab Fragment (TAB-411CT-F(E)) | ELISA, Neut | Humanized Fab |
| TAB-412CT-F(E) | Humanized Anti-SOST Recombinant Antibody; Fab Fragment (TAB-412CT-F(E)) | ELISA, Neut | Humanized Fab |
| TAB-413CT-F(E) | Humanized Anti-SOST Recombinant Antibody; Fab Fragment (TAB-413CT-F(E)) | ELISA, Neut | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-558CL | Afuco™ Anti-SOST Recombinant Antibody (AFC-558CL), ADCC Enhanced | ELISA, WB | Humanized IgG1 |
| AFC-TAB-116 | Afuco™ Anti-SOST Recombinant Antibody (AFC-TAB-116), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | Human IgG1, κ |
| AFC-TAB-115 | Afuco™ Anti-SOST ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-115) | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-384CT | Llama Anti-SOST Recombinant Antibody (TAB-384CT) | WB, ELSA, FC | Llama VHH |
| TAB-385CT | Anti-Human SOST Single Domain Antibody (TAB-385CT), Research Grade Biosimilar | WB, ELSA, FC | Single domain antibody |
| TAB-386CT | Anti-Human SOST Single Domain Antibody (TAB-386CT), Research Grade Biosimilar | WB, ELSA, FC | Single domain antibody |
| TAB-387CT | Anti-Human SOST Single Domain Antibody (TAB-387CT), Research Grade Biosimilar | WB, ELSA, FC | Single domain antibody |
| TAB-388CT | Anti-Human SOST Single Domain Antibody (TAB-388CT), Research Grade Biosimilar | WB, ELSA, FC | Single domain antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-393CT | Anti-Human SOST Recombinant Antibody (DM4) | ELISA, Neut | Human antibody |
| TAB-394CT | Human Anti-SOST Recombinant Antibody (TAB-394CT) | ELISA, Neut | Human IgG2, κ |
| TAB-395CT | Human Anti-SOST Recombinant Antibody (TAB-395CT) | ELISA, Neut | Human IgG2, κ |
| TAB-396CT | Human Anti-SOST Recombinant Antibody (TAB-396CT) | ELISA, Neut | Human IgG2, κ |
| TAB-397CT | Human Anti-SOST Recombinant Antibody (TAB-397CT) | ELISA | Human IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4434 | Hi-Affi™ Recombinant Rabbit Anti-SOST Monoclonal Antibody (SI527DS) | ELISA | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0461-CN-S(P) | Human Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0461-CN-S(P)) | ELISA, Block | Human scFv |
| HPAB-0462-CN-S(P) | Human Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0462-CN-S(P)) | ELISA, Block | Humanized scFv |
| HPAB-0463-CN-S(P) | Human Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0463-CN-S(P)) | ELISA, Block | Human scFv |
| HPAB-0464-CN-S(P) | Mouse Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0464-CN-S(P)) | ELISA, Block | Mouse scFv |
| HPAB-0467-CN-S(P) | Mouse Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0467-CN-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1122LY-F(E) | Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-1122LY-F(E)) | ELISA | Humanized Fab |
| HPAB-1123LY-F(E) | Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-1123LY-F(E)) | ELISA, Block | Humanized Fab |
| HPAB-0579-WJ-F(E) | Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0579-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0580-WJ-F(E) | Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0580-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0581-WJ-F(E) | Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0581-WJ-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-402 | Human Anti-SOST Recombinant Antibody (PABC-402) | SPR, ELISA, IHC, Neut | Human IgG1 |
| HPAB-1128-CN | Human Anti-SOST Recombinant Antibody (clone Ab1) | WB, ELISA | Human IgG |
| HPAB-1129-CN | Human Anti-SOST Recombinant Antibody (clone Ab2) | WB, ELISA | Human IgG |
| HPAB-1130-CN | Human Anti-SOST Recombinant Antibody (clone Ab3) | WB, ELISA | Human IgG |
| HPAB-0920-WJ | Human Anti-SOST Recombinant Antibody (HPAB-0920-WJ) | ELISA | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY246 | AbPlus™ Anti-SOST Magnetic Beads (VS-0424-XY2446) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY180 | Human Anti-SOST scFv-Fc Chimera (VS-0425-FY180) | Inhib, ELISA | Human IgG2, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC297 | Recombinant Anti-SOST Eliminating Antibody, pH-Sensitive (VS-0625-YC297) | Antigen-Sweeping In Vivo. | Mouse IgG4 kappa |
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