Human Anti-SOST Recombinant Antibody (TAB-116)
CAT#: TAB-116
This product is a recombinant Human antibody that recognizes SOST. The antibody was purified by affinity chromatography.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Group enriched (HaCaT, SuSa)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167941-SOST
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- Human IgG2, κ
- Species Reactivity
- Human
- Applications
- Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
- MW
- 145.9 kDa
- Related Disease
- Postmenopausal women osteoporosis
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Reliable Performance
The Human Anti-SOST Recombinant Antibody has significantly advanced our osteoporosis research. Its specificity and sensitivity are unmatched, providing reliable results every time. The customer support from Creative Biolabs is top-notch, guiding us through the setup to ensure precise application in our assays.
Research Application Versatility
This antibody's versatility across various applications like IF, ELISA, and FC makes it indispensable for comprehensive bone metabolism studies. Its robust construction ensures durability and high fidelity results.
Efficient for Osteoporosis Research
Targeting the SOST protein with this antibody has streamlined our osteoporosis research projects. Its efficiency in identifying sclerostin activity has provided invaluable data for our therapeutic development endeavors.
Q&As
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What is the primary application of the Human Anti-SOST Recombinant Antibody in research?
A: The Human Anti-SOST Recombinant Antibody is primarily used in immunological assays such as immunofluorescence (IF), immunoprecipitation (IP), neutralization (Neut), functional studies (FuncS), enzyme-linked immunosorbent assay (ELISA), flow cytometry (FC), and immunocytochemistry (ICC). It helps researchers investigate the expression and role of the SOST protein, particularly in studies related to bone metabolism and diseases like osteoporosis.
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How can the Human Anti-SOST Recombinant Antibody aid in the study of osteoporosis?
A: This antibody targets sclerostin, a protein that negatively regulates bone formation. By binding to sclerostin, researchers can study its role in the signaling pathways that contribute to osteoporosis, particularly in postmenopausal women. Understanding this interaction helps in developing therapies to counteract bone loss.
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In which other diseases, apart from osteoporosis, might the Human Anti-SOST Recombinant Antibody be beneficial for research?
A: The antibody is beneficial in researching diseases that involve bone metabolism abnormalities, including sclerosteosis and Van Buchem disease, by allowing scientists to study the regulation and modulation of bone growth at the molecular level.
View the frequently asked questions answered by Creative Biolabs Support.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-116, RRID: AB_3111820)
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "SOST"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-115 | Anti-Human SOST Recombinant Antibody (TAB-115) | FuncS, IF, Neut, ELISA, FC, IP, ICC | IgG4 - kappa |
| TAB-411CT | Humanized Anti-SOST Recombinant Antibody (TAB-411CT) | ELISA, Neut | Humanized antibody |
| TAB-412CT | Humanized Anti-SOST Recombinant Antibody (TAB-412CT) | ELISA, Neut | Humanized antibody |
| TAB-413CT | Humanized Anti-SOST Recombinant Antibody (TAB-413CT) | ELISA, Neut | Humanized antibody |
| TAB-411CT-S(P) | Humanized Anti-SOST Recombinant Antibody; scFv Fragment (TAB-411CT-S(P)) | ELISA, Neut | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-558CL | Afuco™ Anti-SOST Recombinant Antibody (AFC-558CL), ADCC Enhanced | ELISA, WB | Humanized IgG1 |
| AFC-TAB-116 | Afuco™ Anti-SOST Recombinant Antibody (AFC-TAB-116), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | Human IgG1, κ |
| AFC-TAB-115 | Afuco™ Anti-SOST ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-115) | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-384CT | Llama Anti-SOST Recombinant Antibody (TAB-384CT) | WB, ELSA, FC | Llama VHH |
| TAB-385CT | Anti-Human SOST Single Domain Antibody (TAB-385CT), Research Grade Biosimilar | WB, ELSA, FC | Single domain antibody |
| TAB-386CT | Anti-Human SOST Single Domain Antibody (TAB-386CT), Research Grade Biosimilar | WB, ELSA, FC | Single domain antibody |
| TAB-387CT | Anti-Human SOST Single Domain Antibody (TAB-387CT), Research Grade Biosimilar | WB, ELSA, FC | Single domain antibody |
| TAB-388CT | Anti-Human SOST Single Domain Antibody (TAB-388CT), Research Grade Biosimilar | WB, ELSA, FC | Single domain antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-393CT-S(P) | Anti-Human SOST Recombinant Antibody scFv Fragment (DM4) | ELISA, Neut | Human antibody |
| TAB-394CT-S(P) | Human Anti-SOST Recombinant Antibody; scFv Fragment (TAB-394CT-S(P)) | ELISA, Neut | Human scFv |
| TAB-395CT-S(P) | Human Anti-SOST Recombinant Antibody; scFv Fragment (TAB-395CT-S(P)) | ELISA, Neut | Human scFv |
| TAB-396CT-S(P) | Human Anti-SOST Recombinant Antibody; scFv Fragment (TAB-396CT-S(P)) | ELISA, Neut | Human scFv |
| TAB-397CT-S(P) | Human Anti-SOST Recombinant Antibody; scFv Fragment (TAB-397CT-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4434 | Hi-Affi™ Recombinant Rabbit Anti-SOST Monoclonal Antibody (SI527DS) | ELISA | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0342-YC | Human Anti-SOST Recombinant Antibody (HPAB-0342-YC) | Neut, FuncS | Humanized IgG |
| HPAB-0343-YC | Mouse Anti-SOST Recombinant Antibody (HPAB-0343-YC) | FuncS | Mouse IgG |
| HPAB-0344-YC | Human Anti-SOST Recombinant Antibody (HPAB-0344-YC) | ELISA, FuncS | Human IgG2, κ |
| HPAB-0461-CN | Human Anti-SOST Recombinant Antibody (HPAB-0461-CN) | ELISA, Block | Humanized IgG |
| PABC-402 | Human Anti-SOST Recombinant Antibody (PABC-402) | SPR, ELISA, IHC, Neut | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0461-CN-S(P) | Human Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0461-CN-S(P)) | ELISA, Block | Human scFv |
| HPAB-0462-CN-S(P) | Human Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0462-CN-S(P)) | ELISA, Block | Humanized scFv |
| HPAB-1128-CN-S(P) | Human Anti-SOST Recombinant Antibody (clone Ab1); scFv Fragment | WB, ELISA | Human scFv |
| HPAB-1129-CN-S(P) | Human Anti-SOST Recombinant Antibody (clone Ab2); scFv Fragment | WB, ELISA | Human scFv |
| HPAB-1130-CN-S(P) | Human Anti-SOST Recombinant Antibody (clone Ab3); scFv Fragment | WB, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1122LY-F(E) | Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-1122LY-F(E)) | ELISA | Humanized Fab |
| HPAB-1123LY-F(E) | Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-1123LY-F(E)) | ELISA, Block | Humanized Fab |
| HPAB-1128-CN-F(E) | Human Anti-SOST Recombinant Antibody (clone Ab1); Fab Fragment | WB, ELISA | Human Fab |
| HPAB-1129-CN-F(E) | Human Anti-SOST Recombinant Antibody (clone Ab2); Fab Fragment | WB, ELISA | Human Fab |
| HPAB-1130-CN-F(E) | Human Anti-SOST Recombinant Antibody (clone Ab3); Fab Fragment | WB, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY246 | AbPlus™ Anti-SOST Magnetic Beads (VS-0424-XY2446) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY180 | Human Anti-SOST scFv-Fc Chimera (VS-0425-FY180) | Inhib, ELISA | Human IgG2, scFv-Fc |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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