What applications can this antibody be used for?

This antibody is suitable for immunoassay techniques such as Western Blot (WB), ELISA, and Flow Cytometry (FC). It targets SOST, a glycoprotein involved in bone formation regulation, making it a valuable tool for research into bone diseases like osteoporosis.

Anti-Human SOST Single Domain Antibody (TAB-391CT), Research Grade Biosimilar

CAT#: TAB-391CT

Recombinant single domain antibody that specifically binds to sclerostin. The antibody can be potentially used for the prevention and treatment of bone diseases and disorders.

Gene Expression

RNA Expression Figure 1 RNA cell line category: Group enriched (HaCaT, SuSa)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167941-SOST

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Specifications

Immunogen
Recombinant human sclerostin

Host Species
Llama

Derivation
Llama immuniezd library

Type
Single domain antibody

Specificity
Human

Species Reactivity
Human, Mouse

Clone
TAB-391CT

Applications
Used for immunoassay techniques such as: Western Blot; ELSA; Flow Cytometry

Related Disease
Multiple myeloma, osteoporosis, osteopenia, Paget's Disease, bone fracture, bone loss.

Target

Alternative Names
SOST; sclerostin; CDD; VBCH; SOST1; Scl-mAb; Scl-Ab

Gene ID
50964

UniProt ID
Q9BQB4

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Breast cancer biomarkers at key points during disease progression

Unique Single Domain Antibody

This Llama-derived single domain antibody is a unique tool. We utilized it for Western Blot and Flow Cytometry to detect Sclerostin. Its small size and high stability make it an interesting candidate for our bone disease research models.

Effective Sclerostin Binder

We are studying the Wnt signaling pathway and needed a reliable binder for SOST. This recombinant antibody binds specifically to human Sclerostin and works well in ELISA. It has been instrumental in our studies of bone morphogenetic protein antagonists.

Q&As

What applications can this antibody be used for?

A: This antibody is suitable for immunoassay techniques such as Western Blot (WB), ELISA, and Flow Cytometry (FC). It targets SOST, a glycoprotein involved in bone formation regulation, making it a valuable tool for research into bone diseases like osteoporosis.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-391CT.pdf

MSDS

MSDS - TAB-391CT.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

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TAB-385CT	Anti-Human SOST Single Domain Antibody (TAB-385CT), Research Grade Biosimilar	WB, ELSA, FC	Single domain antibody

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TAB-386CT	Anti-Human SOST Single Domain Antibody (TAB-386CT), Research Grade Biosimilar	WB, ELSA, FC	Single domain antibody

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TAB-387CT	Anti-Human SOST Single Domain Antibody (TAB-387CT), Research Grade Biosimilar	WB, ELSA, FC	Single domain antibody

CAT	Product Name	Application	Type
TAB-388CT	Anti-Human SOST Single Domain Antibody (TAB-388CT), Research Grade Biosimilar	WB, ELSA, FC	Single domain antibody

CAT	Product Name	Application	Type
TAB-393CT	Anti-Human SOST Recombinant Antibody (DM4)	ELISA, Neut	Human antibody

CAT	Product Name	Application	Type
TAB-394CT	Human Anti-SOST Recombinant Antibody (TAB-394CT)	ELISA, Neut	Human IgG2, κ

CAT	Product Name	Application	Type
TAB-395CT	Human Anti-SOST Recombinant Antibody (TAB-395CT)	ELISA, Neut	Human IgG2, κ

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TAB-396CT	Human Anti-SOST Recombinant Antibody (TAB-396CT)	ELISA, Neut	Human IgG2, κ

CAT	Product Name	Application	Type
TAB-397CT	Human Anti-SOST Recombinant Antibody (TAB-397CT)	ELISA	Human IgG1, κ

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TAB-411CT	Humanized Anti-SOST Recombinant Antibody (TAB-411CT)	ELISA, Neut	Humanized antibody

CAT	Product Name	Application	Type
TAB-412CT	Humanized Anti-SOST Recombinant Antibody (TAB-412CT)	ELISA, Neut	Humanized antibody

CAT	Product Name	Application	Type
MOB-1840CT	Recombinant Mouse anti-Human SOST Monoclonal antibody (NN0667-0O24)	WB, ELISA

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MOR-4434	Hi-Affi™ Recombinant Rabbit Anti-SOST Monoclonal Antibody (SI527DS)	ELISA	IgG

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HPAB-0342-YC	Human Anti-SOST Recombinant Antibody (HPAB-0342-YC)	Neut, FuncS	Humanized IgG

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HPAB-0343-YC	Mouse Anti-SOST Recombinant Antibody (HPAB-0343-YC)	FuncS	Mouse IgG

CAT	Product Name	Application	Type
HPAB-0344-YC	Human Anti-SOST Recombinant Antibody (HPAB-0344-YC)	ELISA, FuncS	Human IgG2, κ

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HPAB-0342-YC-S(P)	Human Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0342-YC-S(P))	Neut, FuncS	Humanized scFv

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HPAB-0343-YC-S(P)	Mouse Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0343-YC-S(P))	FuncS	Mouse scFv

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HPAB-0344-YC-S(P)	Human Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0344-YC-S(P))	ELISA, FuncS	Human scFv

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HPAB-0342-YC-F(E)	Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0342-YC-F(E))	Neut, FuncS	Humanized Fab

CAT	Product Name	Application	Type
HPAB-0343-YC-F(E)	Mouse Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0343-YC-F(E))	FuncS	Mouse Fab

CAT	Product Name	Application	Type
HPAB-0344-YC-F(E)	Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0344-YC-F(E))	ELISA, FuncS	Human Fab

CAT	Product Name	Application	Type
HPAB-0461-CN-S(P)	Human Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0461-CN-S(P))	ELISA, Block	Human scFv

CAT	Product Name	Application	Type
HPAB-0462-CN-S(P)	Human Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0462-CN-S(P))	ELISA, Block	Humanized scFv

CAT	Product Name	Application	Type
HPAB-0461-CN-F(E)	Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0461-CN-F(E))	ELISA, Block	Human Fab

CAT	Product Name	Application	Type
HPAB-0462-CN-F(E)	Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0462-CN-F(E))	ELISA, Block	Humanized Fab

CAT	Product Name	Application	Type
AFC-TAB-116	Afuco™ Anti-SOST Recombinant Antibody (AFC-TAB-116), ADCC Enhanced	IF, IP, Neut, FuncS, ELISA, FC	Human IgG1, κ

CAT	Product Name	Application	Type
AFC-TAB-115	Afuco™ Anti-SOST ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-115)	FuncS, IF, Neut, ELISA, FC, IP	ADCC enhanced antibody

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VS-0424-XY246	AbPlus™ Anti-SOST Magnetic Beads (VS-0424-XY2446)	IP, Protein Purification

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VS-0425-FY180	Human Anti-SOST scFv-Fc Chimera (VS-0425-FY180)	Inhib, ELISA	Human IgG2, scFv-Fc

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VS-0625-YC297	Recombinant Anti-SOST Eliminating Antibody, pH-Sensitive (VS-0625-YC297)	Antigen-Sweeping In Vivo.	Mouse IgG4 kappa

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VS-0825-YC314	SmartAb™ Recombinant Anti-SOST pH-dependent Antibody (VS-0825-YC314)	Neut	Human IgG

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