Recombinant Human Anti-Staphylococcal enterotoxin B (SEB) Antibody (3E2)

CAT#: PABL-336

Recombinant Human Antibody (3E2) is capable of binding to Staphylococcal enterotoxin B (SEB), expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-Staphylococcal enterotoxin B (SEB) mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-Staphylococcal enterotoxin B (SEB) mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.

Published Data
Figure 1 anti-SEB monoclonal antibody Western blot analysis. Figure 2 Relative affinity of SEB antibody to protein. Figure 3 murine anti-SEB monoclonal antibody 3E2, 1A5, 4A3, 3C1 and inhibition of SEB-induced proliferation of T lymphocytes. Figure 4 Inhibition of murine anti-SEB monoclonal 1A5, 4A3, 3C1, 3E2 and SEB in vitro on PBMC cytokine release. Figure 5 murine anti-SEB monoclonal antibody 3E2, 1A5, 4A3, 3C1 and toxic shock syndrome in SEB-induced model can effectively improve the survival rate of mice. Figure 6 Inhibition of cytokine murine anti-SEB monoclonal antibody 3E2 of mouse serum 1A5,4A3,3C1 and SEB induced in vivo.

Specifications

  • Immunogen
  • S. aureus Staphylococcal enterotoxin B
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • IgG
  • Specificity
  • Tested positive against native S. aureus SEB
  • Species Reactivity
  • S. aureus
  • Clone
  • 3E2
  • Applications
  • WB, ELISA, Inhib, Neut, FuncS

Product Property

  • Purity
  • >95% by SDS-PAGE and HPLC analysis
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Applications

  • Application Notes
  • The antibody was validated for Western Blot, ELISA, Inhibition and Function Assay. For details, refer to Published Data.

Target

  • Alternative Names
  • SEB; Staphylococcal enterotoxin B; enterotoxin type B
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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